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Titolo:
Morphologic abnormalities in the brain of chronically hemodialyzed patients without cerebrovascular disease
Autore:
Kamata, T; Hishida, A; Takita, T; Sawada, K; Ikegaya, N; Maruyama, Y; Miyajima, H; Kaneko, E;
Indirizzi:
Hamamatsu Univ, Sch Med, Dept Med 1, Hamamatsu, Shizuoka 4313192, Japan Hamamatsu Univ Hamamatsu Shizuoka Japan 4313192 , Shizuoka 4313192, Japan Maruyama Hosp, Hamamatsu, Shizuoka, Japan Maruyama Hosp Hamamatsu Shizuoka Japan Hosp, Hamamatsu, Shizuoka, Japan
Titolo Testata:
AMERICAN JOURNAL OF NEPHROLOGY
fascicolo: 1, volume: 20, anno: 2000,
pagine: 27 - 31
SICI:
0250-8095(200001/02)20:1<27:MAITBO>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL COMPUTED-TOMOGRAPHY; COGNITIVE FUNCTION; DIALYSIS PATIENTS; BLOOD-FLOW; ATROPHY;
Keywords:
cerebral atrophy; hemodialysis; anemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Kamata, T Hamamatsu Univ, Sch Med, Dept Med 1, Handa Cho, Hamamatsu, Shizuoka 4313192, Japan Hamamatsu Univ Handa Cho Hamamatsu Shizuoka Japan 4313192 Japan
Citazione:
T. Kamata et al., "Morphologic abnormalities in the brain of chronically hemodialyzed patients without cerebrovascular disease", AM J NEPHR, 20(1), 2000, pp. 27-31

Abstract

In this study, the authors evaluated the cerebral atrophy in 56 chronic hemodialyzed patients, who did not have clinical episodes or radiologic findings of cerebrovascular diseases, and 42 controls. Using computed tomography(CT) images, brain atrophy index (BAI), the proportion of subarachnoidal plus ventricular space in the cranial cavity, and ventricular area index (VAI), percent area of ventricle in the brain, were calculated, CT of the brain demonstrated an age-dependent increase in BAI in both hemodialyzed patients and controls. BAI and VAI were greater in hemodialyzed patients than healthy controls and the difference was significant at ages under 60 years in BAI and at ages less than 50 years in VAI. The atrophy of the frontal partsof the brain in patients on hemodialysis for 10 years or more was significantly greater than in patients dialyzed for less than 10 years. There was asignificant negative correlation between BAI or VAI and hematocrit. These findings indicate that renal failure or hemodialysis itself might cause cerebral atrophy, and that the cerebral atrophy is more prominent in patients on hemodialysis for a long duration and with low hematocrit. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:08:56