Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Visual event-related potentials in children with phenylketonuria
Autore:
Henderson, RM; McCulloch, DL; Herbert, AM; Robinson, PH; Taylor, MJ;
Indirizzi:
Glasgow Caledonian Univ, Dept Vis Sci, Glasgow G4 0BA, Lanark, Scotland Glasgow Caledonian Univ Glasgow Lanark Scotland G4 0BA , Lanark, Scotland Univ N Texas, Dept Psychol, Denton, TX 76203 USA Univ N Texas Denton TX USA 76203 exas, Dept Psychol, Denton, TX 76203 USA Royal Hosp Sick Children, Glasgow G3 8SJ, Lanark, Scotland Royal Hosp SickChildren Glasgow Lanark Scotland G3 8SJ Lanark, Scotland Fac Med Rangueil, CERCO, Toulouse, France Fac Med Rangueil Toulouse France Med Rangueil, CERCO, Toulouse, France
Titolo Testata:
ACTA PAEDIATRICA
fascicolo: 1, volume: 89, anno: 2000,
pagine: 52 - 57
SICI:
0803-5253(200001)89:1<52:VEPICW>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOKED-POTENTIALS; PHENYLALANINE RESTRICTION; BRAIN MRI; ADOLESCENTS; HYPERPHENYLALANINEMIA; LESIONS; P300;
Keywords:
event-related potentials; phenylalanine; phenylketonuria; reaction time; P3; visual evoked potentials;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Henderson, RM Glasgow Caledonian Univ, Dept Vis Sci, Cowcaddens Rd, Glasgow G4 0BA, Lanark, Scotland Glasgow Caledonian Univ Cowcaddens Rd Glasgow Lanark Scotland G4 0BA
Citazione:
R.M. Henderson et al., "Visual event-related potentials in children with phenylketonuria", ACT PAEDIAT, 89(1), 2000, pp. 52-57

Abstract

Visual event-related potentials (ERPs) were examined in 16 children (aged 5-14 y) with phenylketonuria (PKU) and 16 age- and sex-matched controls. Lifetime median measures of phenylalanine (Phe) were 230-460 mu mol/l. The most recent Phe levels were 56-624 mu mol/l. ERPs were recorded whilst the children performed a discrimination task. All stimuli were square wave gratings degree, which appeared for 33 ms. A response to an infrequent grating that differed in orientation or spatial frequency was required. The older children with PKU had a delay in the first peak (P1) of the ERP, and age-related changes in the amplitude of P1. There was attenuation of the second peakacross age groups in PKU. There was no evidence of reduced response accuracy or longer reaction times in children with PKU, Latencies of the cognitive P3 were not delayed in PKU. The delayed early peaks are consistent with previous studies that have shown delayed visual evoked potentials in PKU. The lack of differences in reaction time and P3 may be due to relatively goodPhe control in children with PKU, or to the simplicity of the task. Suggestions are made for future ERP studies of PKU.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 00:22:44