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Titolo:
The intraoperative gamma probe: Basic principles and choices available
Autore:
Zanzonico, P; Heller, S;
Indirizzi:
Mem Sloan Kettering Canc Ctr, Nucl Med Serv, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA Montefiore Med Ctr, Dept Nucl Med, Bronx, NY 10467 USA Montefiore Med CtrBronx NY USA 10467 Dept Nucl Med, Bronx, NY 10467 USA
Titolo Testata:
SEMINARS IN NUCLEAR MEDICINE
fascicolo: 1, volume: 30, anno: 2000,
pagine: 33 - 48
SICI:
0001-2998(200001)30:1<33:TIGPBP>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
NODE LOCALIZATION; SURGICAL PROBE; BREAST-CANCER; POSITRON; MELANOMA; SURGERY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Zanzonico, P Mem Sloan Kettering Canc Ctr, Nucl Med Serv, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr 1275 York Ave New York NY USA 10021
Citazione:
P. Zanzonico e S. Heller, "The intraoperative gamma probe: Basic principles and choices available", SEM NUC MED, 30(1), 2000, pp. 33-48

Abstract

By taking advantage of the proximity to radioactive sentinel nodes and occult tumors achievable in an operative setting, intraoperative probes are becoming increasingly important in the surgical management of cancer. This article begins with a discussion of the statistical limitations of radiation detection and measurement and of the key performance parameters (sensitivity, energy resolution, and spatial resolution) that characterize detectors. The basic design and operating principle of radiation detectors used in intraoperative probes, scintillation and semiconductor detectors, are then reviewed. Scintillation detector-based intraoperative probes, generally using a NaI(TI) or a CsI(TI) crystal connected to a photomultiplier tube by a fiberoptic cable, have the advantages of reliability, relatively low cost, andhigh sensitivity, especially for medium- to high-energy photons. Disadvantages include poor energy resolution and scatter rejection, and bulkiness. Semiconductor (CdZn, CdZnTe, HgI2)-based probes are compact and have excellent energy resolution and scatter rejection, but with complex energy spectrareflecting charge-carrier trapping. Their main disadvantage is lower sensitivity. The performance parameters of various commercially available intraoperative probes are then compared. The article concludes with a discussion of the practical considerations in selecting and using intraoperative probes, including ergonomic and other design features, as well as performance parameters. Copyright (C) 2000 by W.B. Saunders Company.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 20:20:32