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Titolo:
Relationship between serotonin and the Temperament and Character Inventory
Autore:
Peirson, AR; Heuchert, JW; Thomala, L; Berk, M; Plein, H; Cloninger, CR;
Indirizzi:
Univ Witwatersrand, Dept Psychol, ZA-2050 Wits, South Africa Univ Witwatersrand Wits South Africa ZA-2050 ZA-2050 Wits, South Africa Univ Witwatersrand, Sch Med, ZA-2050 Wits, South Africa Univ Witwatersrand Wits South Africa ZA-2050 ZA-2050 Wits, South Africa Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA WashingtonUniv St Louis MO USA 63110 pt Psychiat, St Louis, MO 63110 USA
Titolo Testata:
PSYCHIATRY RESEARCH
fascicolo: 1, volume: 89, anno: 1999,
pagine: 29 - 37
SICI:
0165-1781(199912)89:1<29:RBSATT>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIDIMENSIONAL PERSONALITY QUESTIONNAIRE; CALCIUM MOBILIZATION; SENSATION SEEKING; PLATELETS; DISORDERS; METABOLITES; INHIBITORS; MODEL;
Keywords:
serotonin; personality; harm avoidance; Temperament and Character Inventory;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Peirson, AR POB 85109, ZA-2029 Emmarentia, South Africa POB 85109 Emmarentia South Africa ZA-2029 ntia, South Africa
Citazione:
A.R. Peirson et al., "Relationship between serotonin and the Temperament and Character Inventory", PSYCHIAT R, 89(1), 1999, pp. 29-37

Abstract

The unified biosocial theory of personality, proposed by Cloninger; conceptualises personality as a combination of heritable, neurobiologically basedtraits (temperament dimensions), and traits reflecting sociocultural learning (character dimensions). The temperament dimensions are thought to be related to activity in specific central neurotransmitter systems. The relationship of the dimensions of the Temperament and Character Inventory, particularly harm avoidance (HA), and platelet 5-HT2 receptor sensitivity was investigated in a sample of undergraduate student volunteers (N = 49). Serotonin-receptor binding results in Ca2+ release from intracellular stores. The concentration of serotonin required to produce half maximal Ca2+: response (EC50) is indicative of 5-HT2 receptor sensitivity such that the lower the EC50 serotonin concentration, the greater the 5-HT2 receptor sensitivity. A significant inverse correlation was found between HA and EC50 (r = -0.644, P < 0.001). Self-directedness was also significantly correlated with EC50 (r = 0.391, P = 0.005). Novelty seeking, a personality trait similar to sensation seeking, was not significantly correlated with serotonin. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:41:05