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Titolo:
Quantitative ultrasound and symptomatic vertebral fracture risk in Chinesewomen
Autore:
Kung, AWC; Luk, KDK; Chu, LW; Tang, GWK;
Indirizzi:
Univ Hong Kong, Dept Med, Queen Mary Hosp, Hong Kong, Peoples R China UnivHong Kong Hong Kong Peoples R China sp, Hong Kong, Peoples R China Univ Hong Kong, Dept Orthopaed Surg, Queen Mary Hosp, Hong Kong, Peoples RChina Univ Hong Kong Hong Kong Peoples R China osp, Hong Kong, Peoples RChina Univ Hong Kong, Dept Obstet & Gynaecol, Queen Mary Hosp, Hong Kong, Peoples R China Univ Hong Kong Hong Kong Peoples R China sp, Hong Kong, Peoples R China
Titolo Testata:
OSTEOPOROSIS INTERNATIONAL
fascicolo: 6, volume: 10, anno: 1999,
pagine: 456 - 461
SICI:
0937-941X(1999)10:6<456:QUASVF>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE MASS; HIP-FRACTURES; OS CALCIS; ATTENUATION; OSTEOPOROSIS; DENSITOMETRY; PREDICTION; CALCANEUS; DENSITY; SITES;
Keywords:
Chinese; quantitative ultrasound; vertebral fracture risk;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Kung, AWC Univ Hong Kong, Dept Med, Queen Mary Hosp, 102 Pokfulam Rd, HongKong, Peoples R China Univ Hong Kong 102 Pokfulam Rd Hong Kong Peoples R China China
Citazione:
A.W.C. Kung et al., "Quantitative ultrasound and symptomatic vertebral fracture risk in Chinesewomen", OSTEOPOR IN, 10(6), 1999, pp. 456-461

Abstract

Quantitative ultrasound (QUS) is emerging as a simple, inexpensive and noninvasive method for assessing bone quality and assessing fracture risk. We assessed the usefulness of a contact calcaneal ultra-sonometer by studying normal premenopausal women (group I, n = 53), normal postmenopausal women (group II, n = 198), and osteoporotic women without (group III, It = 141) and with vertebral fractures (group IV, n = 53). The osteoporotic subjects had a T-score of the spine or hip neck bone mineral density (BMD) <-2.5 basedon the local Chinese peak young mean values. When compared with postmenopausal controls, mean broadband ultrasound attenuation (BUA), speed of sound (SOS), and quantitative ultrasound index (QUI) were 26%, 2.1% and 25% lowerin women with vertebral fractures (p all <0.005). The correlation coefficients between QUS parameters and BMD of the spine and hip ranged between 0.4and 0.5. The ability of the QUS to discriminate between patients groups was determined based on the mean value of normal premenopausal women in groupI. The mean T-score for women with fractures was -2.87 +/- 1.02 for BUA, -2.54 +/- 0.79 for SOS, -3.17 +/- 0.70 for QUI, -2.65 +/- 0.86 for L2-4 BMD and -2.53 +/- 0.66 for hip neck BMD. After adjustment for age and body massindex, the odds ratio of vertebral fracture was 1.71 (95% CI 1.2-2.6) for each 1 SD reduction in BUA, 2.72 (1.3-5.3) for SOS, 2.58 (1.4-4.6) for QUI,2.33 (1.6-3.3) for L2-4 BMD, 2.09 (1.37-3.20) for femoral neck BMD and 1.88 (1.34-2.92) for total hip BMD. The association between the QUS parametersand vertebral fracture risk persisted even adjustment for BMD, The area under the receiver operating characteristic curve for BUA for vertebral fracture was 0.92, for SOS, QUI, L2-4 BMD and femoral neck BMD was 0.95, and fortotal hip was 0.91.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:37:08