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Titolo:
Evaluation of FDG uptake by renal malignancies (primary tumor or metastases) using a coincidence detection gamma camera
Autore:
Montravers, F; Grahek, D; Kerrou, K; Younsi, N; Doublet, JD; Gattegno, B; Rossert, J; de Beauregard, MAC; Thibault, P; Talbot, JN;
Indirizzi:
Hop Tenon, Nucl Med Serv, F-75020 Paris, France Hop Tenon Paris France F-75020 non, Nucl Med Serv, F-75020 Paris, France Hop Tenon, Serv Urol, F-75020 Paris, France Hop Tenon Paris France F-75020 p Tenon, Serv Urol, F-75020 Paris, France Hop Tenon, Serv Nephrol A, F-75020 Paris, France Hop Tenon Paris France F-75020 on, Serv Nephrol A, F-75020 Paris, France Hop Tenon, Serv Nephrol B, F-75020 Paris, France Hop Tenon Paris France F-75020 on, Serv Nephrol B, F-75020 Paris, France
Titolo Testata:
JOURNAL OF NUCLEAR MEDICINE
fascicolo: 1, volume: 41, anno: 2000,
pagine: 78 - 84
SICI:
0161-5505(200001)41:1<78:EOFUBR>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; CLINICAL ONCOLOGY; CELL CARCINOMA; PET; CANCER;
Keywords:
renal cancer; FDG; coincidence detection gamma camera;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Montravers, F Hop Tenon, Nucl Med Serv, 4 Rue Chine, F-75020 Paris, FranceHop Tenon 4 Rue Chine Paris France F-75020 20 Paris, France
Citazione:
F. Montravers et al., "Evaluation of FDG uptake by renal malignancies (primary tumor or metastases) using a coincidence detection gamma camera", J NUCL MED, 41(1), 2000, pp. 78-84

Abstract

The aim of this study was to evaluate the usefulness of FDG scanning usingan ordinary gamma camera equipped with coincidence detection (CDET) for 2 renal cancer indications: characterization and staging of renal masses before nephrectomy and search for recurrence after nephrectomy. Methods: Between September 1997 and June 1998, a whole-body scan and at least 1 tomoscintigram were obtained on 23 occasions in 22 patients (fasting for at least 6 h) using a Prism-XP 2000 CDET gamma camera;scanning was begun 45 min after intravenous injection of 150-250 MBq FDG. Results: Postoperative histologic evidence was obtained from 13 of 16 patients who underwent FDG using a CDETgamma camera before renal surgery; 4 renal masses did not accumulate FDG (3 true negatives, 1 false-negative), whereas 9 renal tumors accumulated FDG(8 true-positives, 1 false-positive). In the other 3 patients, only 1 extrarenal site of FDG uptake was checked and confirmed on histologic ex-amination: a bone metastasis from renal cell carcinoma in 2 cases and lymph node metastasis from a squamous cell carcinoma (3 true-positives). The primary local and regional staging of the malignant renal tumors was accurate in the9 patients who underwent nephrectomy (8 true-negatives, 1 true-positive). The primary distant staging was positive In 1 case (focus in the chest corresponding to a probable true-positive on follow-up). In the 7 examinations performed because of suspected recurrence of renal cell carcinoma several months after nephrectomy, metastases were visualized by FDG In 4 patients, confirmed by biopsy in 2 patients, and confirmed by conventional imaging or follow-up (or both) in 2 patients, The other 3 patients had negative FDG scans, corresponding to probable true-negative results on follow-up. Conclusion: FDG using a CDET gamma camera can be used effectively for the staging and restaging of renal tumors and might be useful for characterization of the primary renal tumor in doubtful cases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 07:52:33