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Titolo:
Muscle-dependent and hormone-dependent differentiation of the vocal control premotor nucleus robustus archistriatalis and the motornucleus hypoglossus pars tracheosyringealis of the zebra finch
Autore:
Lohmann, R; Gahr, M;
Indirizzi:
Max Planck Inst Behav Physiol, D-82319 Seewiesen, Germany Max Planck Inst Behav Physiol Seewiesen Germany D-82319 ewiesen, Germany
Titolo Testata:
JOURNAL OF NEUROBIOLOGY
fascicolo: 2, volume: 42, anno: 2000,
pagine: 220 - 231
SICI:
0022-3034(20000205)42:2<220:MAHDOT>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
SONG SYSTEM; SEXUAL-DIFFERENTIATION; NEUROTROPHIC FACTOR; MOTOR-NEURONS; CELL-DEATH; BRAIN; MOTONEURONS; EXPRESSION; RECEPTORS; FOREBRAIN;
Keywords:
syringeal musculature; denervation; zebra finch; development; sexual dimorphism; peripheral influence; estrogen;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Gahr, M Free Univ Amsterdam, Inst Neurosci, De Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam De Boelelaan 1087 Amsterdam Netherlands NL-1081 HV
Citazione:
R. Lohmann e M. Gahr, "Muscle-dependent and hormone-dependent differentiation of the vocal control premotor nucleus robustus archistriatalis and the motornucleus hypoglossus pars tracheosyringealis of the zebra finch", J NEUROBIOL, 42(2), 2000, pp. 220-231

Abstract

Sex differences in the vertebrate brain (brain sex) are thought to developowing to the tissue specific action of gonadal hormones similar to the development of secundary sex characteristics of the body. Small sex differences in body anatomy could, however, retrogradely control the sexual differentiation of the central nervous system. This possibility has so far been verified only for motorneuron pools, since the connectivity of sex-specific higher brain areas to the sexual dimorphic periphery is frequently not well known. Here, we tested whether somatic sex differences feed back on higher brain areas by bilateral denervation of the syringeal musculature of zebra finches before, during, and after onset of estrogen-sensitive sexual differentiation of forebrain vocal nuclei such as RA (nucleus robustus archistriatalis). In the zebra finch, the sound-producing musculature (the syrinx), thesyrinx motornucleus hypolossus pars tracheosyringealis (nXIIts), and the RA are much larger in males compared to females. Tract tracing studies revealed that the volume and neuron size distribution of the nXIIts was sexuallydimorphic in intact but not in animals denervated as juveniles. In contrast, the volume of RA. and size of RA neurons of denervated animals were highly sexually dimorphic. Furthermore, estrogen masculinized the RA of denervated females. Thus, sexual differentiation of the RA but not of the nXIIts appears independent of somatic sex differences. The syrinx muscles are, however, important far the soma size of those RA neurons that project to the nXIIts. (C) 2000 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 06:04:15