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Titolo:
Significance of unsuspected celiac disease detected at endoscopy
Autore:
Green, PHR; Shane, E; Rotterdam, H; Forde, KA; Grossbard, L;
Indirizzi:
Columbia Univ, Coll Phys & Surg, Dept Med, New York, NY 10025 USA ColumbiaUniv New York NY USA 10025 urg, Dept Med, New York, NY 10025 USA Columbia Univ, Coll Phys & Surg, Dept Pathol, New York, NY 10025 USA Columbia Univ New York NY USA 10025 , Dept Pathol, New York, NY 10025 USA Columbia Univ, Coll Phys & Surg, Dept Surg, New York, NY 10025 USA Columbia Univ New York NY USA 10025 rg, Dept Surg, New York, NY 10025 USA
Titolo Testata:
GASTROINTESTINAL ENDOSCOPY
fascicolo: 1, volume: 51, anno: 2000,
pagine: 60 - 65
SICI:
0016-5107(200001)51:1<60:SOUCDD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTEN-FREE DIET; VILLOUS ATROPHY; HIGH PREVALENCE; SPRUE; MALIGNANCY; DIAGNOSIS; ANTIBODIES; MORTALITY; FOLDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Green, PHR 161 Ft Washington Ave, New York, NY 10032 USA 161 Ft Washington Ave New York NY USA 10032 York, NY 10032 USA
Citazione:
P.H.R. Green et al., "Significance of unsuspected celiac disease detected at endoscopy", GASTROIN EN, 51(1), 2000, pp. 60-65

Abstract

Background: Endoscopy provides an opportunity to diagnose unsuspected celiac disease. Methods: We prospectively identified patients undergoing endoscopy for reasons other than the evaluation of diarrhea or suspected malabsorption, who had endoscopic signs in the duodenum suggestive of celiac disease and in whom villous atrophy was confirmed. Patients were assessed for nutritional deficiencies, reduced bone density, parameters of calcium metabolism, and malignancies. Results: Nine patients (3 women and 6 men) were identified among 1749 patients undergoing endoscopy between January 1990 and May 1998, representing arate of unsuspected celiac disease of 1 per 194 endoscopies. The duodenal abnormalities were as follows: reduced or absent folds in 6, scalloped folds in 5, mosaic appearance in 3, and mucosal fissures in 2. Assessment revealed iron deficiency in 5, folate deficiency in 1, osteopenia in 4, osteoporosis in 1, and hypocalciuria in 4. Three had malignancies associated with celiac disease, 2 esophageal squamous carcinomas, and 1 jejunal adenocarcinoma. Conclusions: Unsuspected celiac disease can be diagnosed at endoscopy by recognition of changes in the duodenum. When detected, patients have one or more manifestations of the disease. Celiac disease is more common in the United States than previously considered and endoscopy provides an opportunity to establish the diagnosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:01:21