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Titolo:
Evaluation of pancreatic islet cell tumors by fluorine-18 fluorodeoxyglucose positron emission tomography - Comparison with other modalities
Autore:
Nakamoto, Y; Higashi, T; Sakahara, H; Tamaki, N; Itoh, K; Imamura, M; Konishi, J;
Indirizzi:
Kyoto Univ, Grad Sch Med, Dept Nucl Med & Diagnost Imaging, Kyoto 606, Japan Kyoto Univ Kyoto Japan 606 Nucl Med & Diagnost Imaging, Kyoto 606, Japan Kyoto Univ, Grad Sch Med, Dept Surg 1, Kyoto 606, Japan Kyoto Univ KyotoJapan 606 , Grad Sch Med, Dept Surg 1, Kyoto 606, Japan Hokkaido Univ, Dept Nucl Med, Kyoto, Japan Hokkaido Univ Kyoto JapanHokkaido Univ, Dept Nucl Med, Kyoto, Japan
Titolo Testata:
CLINICAL NUCLEAR MEDICINE
fascicolo: 2, volume: 25, anno: 2000,
pagine: 115 - 119
SICI:
0363-9762(200002)25:2<115:EOPICT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
F-18 FLUORODEOXYGLUCOSE; NEUROENDOCRINE TUMORS; PET; CANCER; FDG; CT;
Keywords:
fluorine-18-labeled fluorodeoxyglucose positron emission tomography; imaging; islet cell tumor;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Nakamoto, Y Kyoto Univ Hosp, Dept Nucl Med, Sakyo Ku, 54 Shogoin Kawahara Cho, Kyoto 6068507, Japan Kyoto Univ Hosp 54 Shogoin Kawahara Cho Kyoto Japan 6068507 n
Citazione:
Y. Nakamoto et al., "Evaluation of pancreatic islet cell tumors by fluorine-18 fluorodeoxyglucose positron emission tomography - Comparison with other modalities", CLIN NUCL M, 25(2), 2000, pp. 115-119

Abstract

Purpose: Pancreatic islet cell tumors are potentially malignant tumors andare often difficult to detect with current imaging modalities. Positron emission tomography (PET) using fluorine-18-labeled fluorodeoxyglucose (FDG) is an imaging technique with high sensitivity for malignant tumors. The aimof this study was to assess the feasibility of FDG PET to detect pancreatic islet cell tumors. Methods: Nineteen lesions of histologically proved islet cell tumors were evaluated in 12 patients (5 men, 7 women; ages 22 to 77 years), FDG uptake was analyzed semiquantitatively as a standardized uptake value. The diagnostic accuracy of PET was compared with that of US, CT, and MRI,Results: Of 19 lesions, 8 showed positive PET results (standardized uptakevalue > 2.3), and localization was indicated in 2 lesions. In nine tumors that were not detected by PET, seven were small tumors ranging from 1.5 to 8 mm in diameter and were not identified by other imaging methods, The sensitivity rate of PET was 53%, whereas those of US, CT, and MRI were 53%, 50%, and 53%, respectively,Conclusion: Our data suggest that FDG PET has a limitation in that it doesnot detect some small-sized islet cell tumors, mainly depending on their size, but it has potential utility as a complementary modality for other imaging techniques.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 01:00:57