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Titolo:
Treatment of alloimmune neonatal neutropenia with granulocyte colony-stimulating factor (G-CSF): a report of two new cases
Autore:
Bedu, A; Rohrlich, P; Farnoux, C; Duval, M; Fenneteau, O; Boissinot, C; Pinquier, D; Cartron, J; Vilmer, E; Aujard, Y;
Indirizzi:
Hop Robert Debre, Serv Neonatol, F-75019 Paris, France Hop Robert Debre Paris France F-75019 rv Neonatol, F-75019 Paris, France Hop Robert Debre, ETS AP HP Site Transfusionnel, F-75019 Paris, France HopRobert Debre Paris France F-75019 nsfusionnel, F-75019 Paris, France Hop Robert Debre, Serv Hematol Pediat, F-75019 Paris, France Hop Robert Debre Paris France F-75019 atol Pediat, F-75019 Paris, France Hop Robert Debre, Serv Hematol Biol, F-75019 Paris, France Hop Robert Debre Paris France F-75019 ematol Biol, F-75019 Paris, France Hop Robert Debre, Serv Gynecol Obstet, F-75019 Paris, France Hop Robert Debre Paris France F-75019 ecol Obstet, F-75019 Paris, France Hop Bicetre, ETS AP HP Site Transfusionnel, F-94275 Le Kremlin Bicetre, France Hop Bicetre Le Kremlin Bicetre France F-94275 Le Kremlin Bicetre, France
Titolo Testata:
ARCHIVES DE PEDIATRIE
fascicolo: 12, volume: 6, anno: 1999,
pagine: 1297 - 1301
SICI:
0929-693X(199912)6:12<1297:TOANNW>2.0.ZU;2-K
Fonte:
ISI
Lingua:
FRE
Soggetto:
CONTROLLED TRIAL; NEUTROPHILS; SEPSIS;
Keywords:
infant, newborn; agranulocytosis; immune complex disease; G-CSF;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Bedu, A Hop Robert Debre, Serv Neonatol, 48 Blvd Serurier, F-75019 Paris, France Hop Robert Debre 48 Blvd Serurier Paris France F-75019 is, France
Citazione:
A. Bedu et al., "Treatment of alloimmune neonatal neutropenia with granulocyte colony-stimulating factor (G-CSF): a report of two new cases", ARCH PED, 6(12), 1999, pp. 1297-1301

Abstract

Alloimmune neonatal neutropenia is a rare event. Usually asymptomatic, if may however in some cases result in a severe sepsis. Treatment with recombinant granulocyte colony-stimulating factor (G-CSF) has been recently proposed Case reports. - We report two new cases in infected newborns of a successful treatment of alloimmune neonatal neutropenia with G-CSF, resulting in complete neutrophil recovery in less than 72 hours. Moreover, the treatmentwas well tolerated Conclusion. - The analysis of these two cases and of those previously reported indicates that G-CSF represents the first-choice treatment in this affection when infectious signs are present in the neonate. (C) 1999 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 13:21:46