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Titolo:
Compliance with and dosing of angiotensin-converting-enzyme inhibitors before and after hospitalization
Autore:
Roe, CM; Motheral, BR; Teitelbaum, F; Rich, MW;
Indirizzi:
Express Scripts Inc, Hlth Management Serv, Maryland Hgts, MO 63043 USA Express Scripts Inc Maryland Hgts MO USA 63043 aryland Hgts, MO 63043 USA Univ Arizona, Coll Pharm, Tucson, AZ 85721 USA Univ Arizona Tucson AZ USA85721 rizona, Coll Pharm, Tucson, AZ 85721 USA Washington Univ, Sch Med, St Louis, MO 63130 USA Washington Univ St LouisMO USA 63130 iv, Sch Med, St Louis, MO 63130 USA Barnes Jewish Hosp, Coronary Care Unit, St Louis, MO 63110 USA Barnes Jewish Hosp St Louis MO USA 63110 are Unit, St Louis, MO 63110 USA Barnes Jewish Hosp, Geriatr Cardiol Program, St Louis, MO 63110 USA BarnesJewish Hosp St Louis MO USA 63110 Program, St Louis, MO 63110 USA Barnes Jewish Hosp, Cardiovasc Dis Fellowship Training Program, St Louis, MO 63110 USA Barnes Jewish Hosp St Louis MO USA 63110 Program, St Louis, MO 63110 USA
Titolo Testata:
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
fascicolo: 2, volume: 57, anno: 2000,
pagine: 139 - 145
SICI:
1079-2082(20000115)57:2<139:CWADOA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGESTIVE-HEART-FAILURE; ELDERLY PATIENTS; ADHERENCE; OUTCOMES;
Keywords:
age; angiotensin-converting-enzyme inhibitors; compliance; dosage schedules; heart failure; sex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Roe, CM Express Scripts Inc, Hlth Management Serv, 13900 Riverport Dr, Maryland Hgts, MO 63043 USA Express Scripts Inc 13900 Riverport Dr Maryland Hgts MO USA 63043
Citazione:
C.M. Roe et al., "Compliance with and dosing of angiotensin-converting-enzyme inhibitors before and after hospitalization", AM J HEAL S, 57(2), 2000, pp. 139-145

Abstract

Compliance with and dosing of angiotensin-converting-enzyme (ACE) inhibitors as they occur before and after hospitalization for heart failure were studied, and factors predictive of compliance with and dosing of ACE inhibitors after hospitalization were identified. Two hundred thirty-six patientd hospitalized with heart failure between October 1, 1995, and April 30, 1996, were identified. Compliance with and useand dosing of ACE inhibitors were examined over the 180-day period before admission and the 180-day period after discharge using an integrated pharmacy and medical claims database. Use of an ACE inhibitor was defined as at least one claim for an ACE inhibitor over the period examined, and dosing was assessed by calculating the mean percentage of an adequate daily dose dispensed. Before hospitalization 109 patients (46.2%) used ACE inhibitors, and afterhospitalization 148 (62.7%) used them-a significant increase . ACE inhibitor use before hospitalization was a predictor of postdischarge use. Youngerpatients were more likely to take ACE inhibitors after haspitalization than older ones, and men had better compliance after hospitalization than women. Additional analyses revealed that, among hospitalization patients, compliance was lower in individuals who also took an antidepressant. Dosing increased from 72% to 85% of an adequate daily dose after hospitalization amongpatients who took ACE inhibitors during both prehospitalization and posthospitalization periods. However, almost one third of hospitalized patients stopped taking their ACE inhibitor within six months of hospital discharge. The study found few significanlpredictors of patient compliance after hospitalizationl Dosing of ACE inhibitors before and after hospitalization needs to be improved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 03:38:11