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Titolo:
Caprine genital leiomyosarcoma
Autore:
Whitney, KM; Valentine, BA; Schlafer, DH;
Indirizzi:
Cornell Univ, Coll Vet Med, Dept Biomed Sci, Ithaca, NY 14853 USA Cornell Univ Ithaca NY USA 14853 d, Dept Biomed Sci, Ithaca, NY 14853 USA
Titolo Testata:
VETERINARY PATHOLOGY
fascicolo: 1, volume: 37, anno: 2000,
pagine: 89 - 94
SICI:
0300-9858(200001)37:1<89:CGL>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
SMOOTH-MUSCLE TUMORS;
Keywords:
goats; leiomyosarcoma; Saanen breed; smooth muscle neoplasia; uterus; vagina;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Whitney, KM Cornell Univ, Coll Vet Med, Dept Biomed Sci, Ithaca, NY 14853 USA Cornell Univ Ithaca NY USA 14853 ed Sci, Ithaca, NY 14853 USA
Citazione:
K.M. Whitney et al., "Caprine genital leiomyosarcoma", VET PATH, 37(1), 2000, pp. 89-94

Abstract

An aged Saanen doe was euthanized following repeated severe hemorrhage from the vulva. Necropsy examination revealed mural thickening of tubular genitalia with firm, protruding intralumenal masses containing blood-filled cavitations, and effacement of normal cervical architecture. Histologically, uterine and cervical masses comprised a variably dense population of mildly pleomorphic spindle cells forming interlacing streams supported by variablydense collagenous stroma. Immunoperoxidase staining of neoplastic cells was positive for muscle-specific actin, supporting the diagnosis of low-gradeleiomyosarcoma. Months later, the doe's twin was likewise euthanized due to persistent bleeding from the vulva associated with a large vulvar mass having histopathologic features similar to those of the previous case. The clinical, gross, and histologic findings are similar to five cases of caprinegenital leiomyosarcoma identified in retrospectively analyzed case material. Analysis of caprine tumor accessions over 20 years demonstrated a significantly higher incidence of genital leiomyosarcoma within the Saanen breed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:33:26