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Titolo:
Evaluation of tumor marker S-100 in cerebrospinal fluid from subjects withnonischemic brain pathologies
Autore:
Infante, JR; Torres-Avisbal, M; Martinez, A; Vallejo, JA; Aguilera, C; Contreras, P; Benitez, A; Latre, JM;
Indirizzi:
Hosp U Reina Sofia, Dept Nucl Med, E-14004 Cordoba, Spain Hosp U Reina Sofia Cordoba Spain E-14004 ucl Med, E-14004 Cordoba, Spain Hosp U Reina Sofia, Dept Clin Anal, E-14004 Cordoba, Spain Hosp U Reina Sofia Cordoba Spain E-14004 in Anal, E-14004 Cordoba, Spain
Titolo Testata:
TUMOR BIOLOGY
fascicolo: 1, volume: 21, anno: 2000,
pagine: 38 - 45
SICI:
1010-4283(200001/02)21:1<38:EOTMSI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURON-SPECIFIC ENOLASE; CENTRAL NERVOUS-SYSTEM; MYELIN BASIC-PROTEIN; NEUROLOGICAL DISORDERS; BACTERIAL-MENINGITIS; DAMAGE; SERUM; PATHOPHYSIOLOGY; INFARCTION;
Keywords:
S-100 protein; cerebrospinal fluid; meningitis; brain damage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Infante, JR Hosp U Reina Sofia, Dept Nucl Med, Avda Menendez Pidal S-N, E-14004 Cordoba, Spain Hosp U Reina Sofia Avda Menendez Pidal S-N Cordoba Spain E-14004
Citazione:
J.R. Infante et al., "Evaluation of tumor marker S-100 in cerebrospinal fluid from subjects withnonischemic brain pathologies", TUMOR BIOL, 21(1), 2000, pp. 38-45

Abstract

In order to evaluate the S-100 concentration in cerebrospinal fluid from subjects with nonischemic brain damage, a total of 33 samples were analyzed:11 from subjects in whom no organic disease could be found; 14 from patients with a diagnosis of lymphocytic or bacterial-fungal meningitis, and 8 from patients with acute lymphatic leukemia but no demonstrable signs of meningeal involvement, In all cases, the subjects considered had no previous history of melanoma or ischemic brain damage. The mean levels +/- SEM found for each study group were 1.00 +/- 0.11, 1.67 +/- 0.23 and 1.17 +/- 0.141 mug/l, respectively. Significant differences appeared between the groups when applying the Kruskal-Wallis nonparametric test: (p = 0.035). The highest levels were Found in the meningitis group and were significantly different From those of the control group (p = 0.015). No significant differences were found with regard to age or sex. Based on the pathophysiology of meningitis and on previous studies, the results suggest the existence of brain damage caused by an infection as a possible cause of increased S-100 levels, Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:24:49