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Titolo:
Insights into the transcriptional control of adipocyte differentiation
Autore:
Morrison, RF; Farmer, SR;
Indirizzi:
Boston Univ, Sch Med, Dept Biochem, Boston, MA 02118 USA Boston Univ Boston MA USA 02118 h Med, Dept Biochem, Boston, MA 02118 USA
Titolo Testata:
JOURNAL OF CELLULAR BIOCHEMISTRY
, , anno: 1999, supplemento:, 32-33
pagine: 59 - 67
SICI:
0730-2312(1999):<59:IITTCO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINDING-PROTEIN-ALPHA; ACTIVATED RECEPTOR-GAMMA; GENE-EXPRESSION; PPAR-GAMMA; C/EBP-ALPHA; ADIPOGENESIS; PROMOTER; IDENTIFICATION; FIBROBLASTS; METABOLISM;
Keywords:
adipocytes; transcription; energy metabolism;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Farmer, SR Boston Univ, Sch Med, Dept Biochem, 715 Albany St, Boston, MA 02118 USA Boston Univ 715 Albany St Boston MA USA 02118 ton, MA 02118 USA
Citazione:
R.F. Morrison e S.R. Farmer, "Insights into the transcriptional control of adipocyte differentiation", J CELL BIOC, 1999, pp. 59-67

Abstract

The adipocyte is now known to play an active role in many physiological and pathological processes regarding energy metabolism. Consideration of adipose tissue as an endocrine organ that secretes a variety of unrelated bioactive molecules has broadened our appreciation of adipocyte function to exceed the once considered passive role in lipid metabolism. Growing interest in this tissue has lead to significant advances regarding the molecular basis for adipocyte differentiation. Several diverse families of transcription factors are currently under active investigation for their roles in mediating this complex process. Knowledge concerning the sequence of transcriptional events during adipogenesis and the interplay among adipogenic transcription factors provides a basis for understanding the physiological processes associated with adipose tissue as well as for the development of therapeutic intervention of adipocyte related diseases. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 08:37:18