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Titolo:
EGEA (Epidemiological study on the Genetics and Environment of Asthma, bronchial hyperresponsiveness and atopy) - descriptive characteristics
Autore:
Kauffmann, F; Dizier, MH; Annesi-Maesano, I; Bousquet, J; Charpin, D; Demenais, F; Ecochard, D; Feingold, J; Gormand, F; Grimfeld, A; Lathrop, M; Matran, R; Neukirch, F; Paty, E; Pin, I; Pison, C; Scheinmann, P; Vervloet, D; Lockhart, A;
Indirizzi:
INSERM, U472, F-94807 Villejuif, France INSERM Villejuif France F-94807INSERM, U472, F-94807 Villejuif, France INSERM, U155, Paris, France INSERM Paris FranceINSERM, U155, Paris, France Hop Arnaud de Villeneuve, Montpellier, France Hop Arnaud de Villeneuve Montpellier France eneuve, Montpellier, France Hop St Marguerite, Marseille, France Hop St Marguerite Marseille FranceHop St Marguerite, Marseille, France INSERM, U358, Paris, France INSERM Paris FranceINSERM, U358, Paris, France Hop Lyon Sud, Paris, France Hop Lyon Sud Paris FranceHop Lyon Sud, Paris, France Hop Trousseau, F-75571 Paris, France Hop Trousseau Paris France F-75571Hop Trousseau, F-75571 Paris, France Wellcome Trust Ctr Human Genet, INSERM, U358, Oxford, England Wellcome Trust Ctr Human Genet Oxford England RM, U358, Oxford, England Hop Cochin, F-75674 Paris, France Hop Cochin Paris France F-75674Hop Cochin, F-75674 Paris, France INSERM, U408, Paris, France INSERM Paris FranceINSERM, U408, Paris, France Hop Necker Enfants Malad, Paris, France Hop Necker Enfants Malad Paris France cker Enfants Malad, Paris, France Hop Albert Michallon, Grenoble, France Hop Albert Michallon Grenoble France Albert Michallon, Grenoble, France
Titolo Testata:
CLINICAL AND EXPERIMENTAL ALLERGY
, volume: 29, anno: 1999, supplemento:, 4
pagine: 17 - 21
SICI:
0954-7894(199912)29:<17:E(SOTG>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Keywords:
asthma; atopy; bronchial hyperresponsiveness; environment; epidemiological methods; genetics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Kauffmann, F INSERM, U472, 16 Ave PV Couturier, F-94807 Villejuif, France INSERM 16 Ave PV Couturier Villejuif France F-94807 , France
Citazione:
F. Kauffmann et al., "EGEA (Epidemiological study on the Genetics and Environment of Asthma, bronchial hyperresponsiveness and atopy) - descriptive characteristics", CLIN EXP AL, 29, 1999, pp. 17-21

Abstract

The Epidemiological study on the Genetics and Environment of Asthma (EGEA)was planned to assess genetic, environmental risk factors and their interactions for asthma and for the two related traits of bronchial hyperresponsiveness and atopy. The population examined includes 348 nuclear families ascertained by one asthmatic (213 adult and 135 paediatric probands) and 416 controls, totalling 1847 subjects (EGEA I). Prevalences of asthma. skin prick test response, high IgE and bronchial hyperresponsiveness were for parents, siblings, and offspring of cases intermediate between cases and spouses or controls, both in adults and children, confirming the familial resemblance for asthma and related traits. With an additional sample of 10 families ascertained by two asthmatic siblings (EGEA II), a total of 119 families with two asthmatic siblings has been ascertained for a genome screening.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 07:54:57