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Titolo:
Prostate-specific antigen
Autore:
Brawer, MK;
Indirizzi:
Northwest Hosp, NW Prostate Inst, Seattle, WA 98133 USA Northwest Hosp Seattle WA USA 98133 Prostate Inst, Seattle, WA 98133 USA
Titolo Testata:
SEMINARS IN SURGICAL ONCOLOGY
fascicolo: 1, volume: 18, anno: 2000,
pagine: 3 - 9
SICI:
8756-0437(200001/02)18:1<3:PA>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEEDLE-BIOPSY; RECTAL EXAMINATION; PREDICTIVE VALUE; CANCER DETECTION; TRANSITION ZONE; PSA DENSITY; SERUM; CARCINOMA; MEN; AGE;
Keywords:
prostate-specific antigen; prostatic neoplasms; carcinoma; prostatic hyperplasia; diagnosis; predictive value of tests; sensitivity and specificity; alpha 1-antichymotripsin; age factors;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Brawer, MK Northwest Hosp, NW Prostate Inst, 1560 N 115th St,Suite 209, Seattle, WA 98133 USA Northwest Hosp 1560 N 115th St,Suite 209 Seattle WA USA98133 A
Citazione:
M.K. Brawer, "Prostate-specific antigen", SEM SURG ON, 18(1), 2000, pp. 3-9

Abstract

Prostate-specific antigen (PSA) has revolutionized the diagnosis and management of men with prostate cancer. Significant advances have been made since the early development of immunoassays. While PSA is useful for staging and monitoring of established disease, it has shown the greatest utility in the realm of early detection realm. PSA is the most important tumor marker; its importance in evaluating men for the possibility of prostate cancer is irrefutable. Enhancing specificity isa pressing need. In this regard, the recognition of the molecular forms of free PSA and complex PSA have shown the most promise and undoubtedly will result in fewer false-positive PSA testresults. The salient literature is reviewed and commentary made on the current status of PSA with particular emphasis on methods to enhance its specificity in early detection and applications. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 07:07:49