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Titolo:
Beta-adrenergic blockers in mental retardation and developmental disabilities
Autore:
Ruedrich, S; Erhardt, L;
Indirizzi:
Metrohlth Med Ctr, Cleveland, OH 44109 USA Metrohlth Med Ctr Cleveland OHUSA 44109 Med Ctr, Cleveland, OH 44109 USA
Titolo Testata:
MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS
fascicolo: 4, volume: 5, anno: 1999,
pagine: 290 - 298
SICI:
1080-4013(1999)5:4<290:BBIMRA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC-INDUCED AKATHISIA; INTERMITTENT EXPLOSIVE DISORDER; PLACEBO-CONTROLLED TRIAL; SELF-INJURIOUS-BEHAVIOR; ORGANIC BRAIN DISEASE; DOUBLE-BLIND; AGGRESSIVE-BEHAVIOR; BLOCKING-DRUGS; ADRENOCEPTOR ANTAGONISTS; ADJUNCTIVE NADOLOL;
Keywords:
beta-adrenergic blockers; pharmacodynamics; pharmacokinetics; anxiety; aggression; neuroleptic-induced akathisia;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
127
Recensione:
Indirizzi per estratti:
Indirizzo: Ruedrich, S Metrohlth Med Ctr, 2500 Metrohlth Dr, Cleveland, OH 44109 USA Metrohlth Med Ctr 2500 Metrohlth Dr Cleveland OH USA 44109 USA
Citazione:
S. Ruedrich e L. Erhardt, "Beta-adrenergic blockers in mental retardation and developmental disabilities", MENT RET D, 5(4), 1999, pp. 290-298

Abstract

Beta-adrenergic-blocking medications have been hypothesized to benefit persons with a wide variety of neuropsychiatric disorders. Research supports their use in only three areas, however: anxiety disorders with prominent physiological signs, impulsive aggression, and neuroleptic-induced akathisia (NIA). Except for NIA, beta blockers are best used adjunctively, and cannot be considered treatments of choice as monotherapy. These guidelines are applicable to individuals with intellectual disability and psychiatric illnessas well, and beta blockers are generally effective and well tolerated in these persons. Nadolol, a hydrophilic beta blocker, may be preferable for anxiety, whereas propranolol and metoprolol (lipophilic) are more beneficial in treating aggression and NIA. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 12:15:24