Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
RXR gamma gene is expressed by discrete cell columns within the alar plateof the brainstem of the chicken embryo
Autore:
Hoover, F; Kielland, A; Glover, JC;
Indirizzi:
Univ Oslo, Inst Basic Med Sci, Dept Anat, N-0317 Oslo, Norway Univ Oslo Oslo Norway N-0317 sic Med Sci, Dept Anat, N-0317 Oslo, Norway Univ Oslo, Inst Basic Med Sci, Dept Physiol, N-0317 Oslo, Norway Univ Oslo Oslo Norway N-0317 Med Sci, Dept Physiol, N-0317 Oslo, Norway
Titolo Testata:
JOURNAL OF COMPARATIVE NEUROLOGY
fascicolo: 4, volume: 416, anno: 2000,
pagine: 417 - 428
SICI:
0021-9967(20000124)416:4<417:RGGIEB>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURAL CREST CELLS; RETINOIC ACID RECEPTORS; CENTRAL-NERVOUS-SYSTEM; ANAS-PLATYRHYNCHOS L; MESENCEPHALIC NUCLEUS; TRIGEMINAL SYSTEM; BETA TRANSCRIPTS; SPINAL-CORD; REGIONAL DIFFERENCES; BINDING-PROTEINS;
Keywords:
retinoid receptor; vitamin A; hindbrain; neural patterning; neural tube; trigeminal;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Glover, JC Univ Oslo, Inst Basic Med Sci, Dept Anat, POB 1105 Blindern, N-0317 Oslo, Norway Univ Oslo POB 1105 Blindern Oslo Norway N-0317 17 Oslo, Norway
Citazione:
F. Hoover et al., "RXR gamma gene is expressed by discrete cell columns within the alar plateof the brainstem of the chicken embryo", J COMP NEUR, 416(4), 2000, pp. 417-428

Abstract

With in situ hybridization assays, we mapped the distribution of retinoid X receptor gamma (RXR gamma) gene transcripts in the central nervous systemof the chicken embryo. Previous studies have demonstrated the presence of RXR gamma transcripts in migrating neural crest and in neural crest. derivatives throughout the peripheral nervous system, implicating RXR gamma as anearly pan-neural crest marker (Rowe et al. 1991. Development 111:771-778),and in the retina (Hoover et al. 1998. J Comp Neurol 391:204-213). Here wereport the presence of RXR gamma transcripts in discrete regions of the developing neural tube, within the hindbrain, the cerebellar plate, the optictectum, and the diencephalon. At stage 10, when migrating neural crest expresses RXR gamma transcripts, we detect no transcripts in the neural tube. By stage 13, RXR gamma transcripts accumulate to detectable levels along the midline of the posterior optic tectum, where the neural crest-derived sensory neurons of the mesencephalic trigeminal nucleus are located. By stage 15, RXR gamma transcripts also appear in an intermittent longitudinal cell column within the mantle zone of the alar plate of the hindbrain, eventually extending into the cerebellar plate rostrally and into the cervical spinal cord caudally, with a gap at about rhombomere 3. By stage 19, transcriptsappear in a discrete population of cells within the diencephalon. Expression in these cell populations continues until at least stage 22.5, when manyneuron populations have been generated in the hindbrain. The localization of the RXR gamma-positive cells to the mantle zone suggests that they are postmitotic and are probably neurons. Their specific alar locations indicatethat they reside within sensory columns and potential downstream targets, evidently corresponding to some of the central components of the trigeminalsystem. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 08:03:20