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Titolo:
HIV-1 RNA load in needles/syringes from shooting galleries in Miami: a preliminary laboratory report
Autore:
Shapshak, P; Fujimura, RK; Page, JB; Segal, D; Rivers, JE; Yang, J; Shah, SM; Graham, G; Metsch, L; Weatherby, N; Chitwood, DD; McCoy, CB;
Indirizzi:
Univ Miami, Sch Med, HIV Lab, Miami, FL 33136 USA Univ Miami Miami FL USA33136 iami, Sch Med, HIV Lab, Miami, FL 33136 USA Univ Miami, Comprehens Drug Res Ctr, Miami, FL 33136 USA Univ Miami MiamiFL USA 33136 omprehens Drug Res Ctr, Miami, FL 33136 USA Univ Miami, Dept Psychiat & Behav Sci, Miami, FL 33136 USA Univ Miami Miami FL USA 33136 t Psychiat & Behav Sci, Miami, FL 33136 USA Univ Miami, Dept Neurol, Miami, FL 33136 USA Univ Miami Miami FL USA 33136 niv Miami, Dept Neurol, Miami, FL 33136 USA Univ Miami, Dept Pathol, Miami, FL 33136 USA Univ Miami Miami FL USA 33136 niv Miami, Dept Pathol, Miami, FL 33136 USA Univ Miami, Dept Epidemiol & Publ Hlth, Miami, FL 33136 USA Univ Miami Miami FL USA 33136 Epidemiol & Publ Hlth, Miami, FL 33136 USA Univ Miami, Dept Anthropol, Coral Gables, FL 33124 USA Univ Miami Coral Gables FL USA 33124 nthropol, Coral Gables, FL 33124 USA Jackson Mem Hosp, Clin Lab, Miami, FL 33136 USA Jackson Mem Hosp Miami FLUSA 33136 m Hosp, Clin Lab, Miami, FL 33136 USA
Titolo Testata:
DRUG AND ALCOHOL DEPENDENCE
fascicolo: 1-2, volume: 58, anno: 2000,
pagine: 153 - 157
SICI:
0376-8716(20000201)58:1-2<153:HRLINF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; INTRAVENOUS-DRUG-USERS; PERINATAL TRANSMISSION; RISK BEHAVIORS; NEEDLES; TYPE-1; SEROPOSITIVITY; SEROCONVERSION; QUANTITATION; PREVENTION;
Keywords:
injecting drug user; blood; needle/syringe; paraphernalia; shooting gallery; HIV-1 RNA load; AIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Shapshak, P Univ Miami, Sch Med, HIV Lab, Elliott Bldg,Room 2026,1800 NW 10th Ave, Miami, FL 33136 USA Univ Miami Elliott Bldg,Room 2026,1800 NW 10thAve Miami FL USA 33136
Citazione:
P. Shapshak et al., "HIV-1 RNA load in needles/syringes from shooting galleries in Miami: a preliminary laboratory report", DRUG AL DEP, 58(1-2), 2000, pp. 153-157

Abstract

We quantified HIV-1 RNA load in rinses from needles/syringes (N/S) obtained at shooting galleries in Miami and also analyzed the rinses for antibodies for viral proteins. In rinses from 36 N/S that contained visible blood, 14 (39%) had detectable amounts of HIV-1 RNA. Numbers of copies of HIV-I RNAranged from the detection limit (400 copies/ml) to 268,000 copies/ml. We also detected antibodies to HIV-I polypeptides in 34/36 (94%) of rinses fromvisibly contaminated N/S using Western blots specific for the HIV-I proteins. No antibodies were detected in laboratory rinses from six visibly cleanneedles. The presence of HIV-1 RNA in N/S is an important indication of the risk created by N/S sharing as well as by shared paraphernalia and wash waters by injecting drug users. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 04:19:25