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Titolo:
Intercellular IgA dermatosis (IgA pemphigus) - two cases illustrating the clinical heterogeneity of this disorder
Autore:
Harman, KE; Holmes, G; Bhogal, BS; McFadden, J; Black, MM;
Indirizzi:
Univ London Kings Coll, St Thomas Hosp, St Johns Inst Dermatol, London, England Univ London Kings Coll London England ns Inst Dermatol, London, England
Titolo Testata:
CLINICAL AND EXPERIMENTAL DERMATOLOGY
fascicolo: 6, volume: 24, anno: 1999,
pagine: 464 - 466
SICI:
0307-6938(199911)24:6<464:IID(P->2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIBODIES; AUTOANTIGENS; FOLIACEUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Harman, KE Univ London Kings Coll Hosp, Dept Dermatol, Denmark Hill, London SE5 9RS, England Univ London Kings Coll Hosp Denmark Hill London EnglandSE5 9RS
Citazione:
K.E. Harman et al., "Intercellular IgA dermatosis (IgA pemphigus) - two cases illustrating the clinical heterogeneity of this disorder", CLIN EXP D, 24(6), 1999, pp. 464-466

Abstract

IgA pemphigus is rare but may be underdiagnosed. We describe two cases, a 50-year-old female with a pustular eruption resembling subcorneal pustular dermatosis and a 55-year-old male with a pruritic vesiculopustular eruptionsimulating dermatitis herpetiformis. They illustrate the clinical heterogeneity of IgA pemphigus which is likely to reflect differences in autoantigens, analogous to pemphigus vulgaris and pemphigus foliaceus. There is now evidence that IgA pemphigus encompasses at least two subgroups: a subcornealpustular dermatosis (SPD)-type, (see case 1) characterized by subcorneal pustules and autoantibodies to desmocollin 1; and intra-epidermal neutrophilic dermatosis (IEN)-type cases (see case 2) which show intra-epidermal pustules and in whom the autoantigen may be desmoglein 3, the pemphigus vulgaris antigen.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:44:16