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Titolo:
Synthesis and binding studies of some epibatidine analogues
Autore:
Radl, S; Hezky, P; Hafner, W; Budesinsky, M; Hejnova, L;
Indirizzi:
Res Inst Pharm & Biochem, CR-13060 Prague, Czech Republic Res Inst Pharm &Biochem Prague Czech Republic CR-13060 , Czech Republic Acad Sci Czech Republ, Inst Organ Chem & Biochem, CR-16610 Prague, Czech Republic Acad Sci Czech Republ Prague Czech Republic CR-16610 gue, Czech Republic
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 1, volume: 10, anno: 2000,
pagine: 55 - 58
SICI:
0960-894X(20000103)10:1<55:SABSOS>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELECTIVE MUSCARINIC AGONISTS; ANALGESICS; RECEPTORS; POTENT; DERIVATIVES; 5-HT1A;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Radl, S Res Inst Pharm & Biochem, Kourimska 17, CR-13060 Prague, Czech Republic Res Inst Pharm & Biochem Kourimska 17 Prague Czech Republic CR-13060
Citazione:
S. Radl et al., "Synthesis and binding studies of some epibatidine analogues", BIOORG MED, 10(1), 2000, pp. 55-58

Abstract

A series of epibatidine analogues and their positional isomers bearing an 8-azabicyclo[3.2.1]octane moiety is described. Some of the compounds, especially those containing 8-azabicyclo[3.2.1]oct-2-ene moiety show high affinity for the nicotinic cholinergic receptor. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 02:02:33