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Titolo:
Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein
Autore:
Seki, N; Hattori, A; Hayashi, A; Kozuma, S; Sasaki, M; Suzuki, Y; Sugano, S; Muramatsu, M; Saito, T;
Indirizzi:
Natl Inst Radiol Sci, Genome Res Grp, Inage Ku, Chiba 2638555, Japan Natl Inst Radiol Sci Chiba Japan 2638555 Inage Ku, Chiba 2638555, Japan Helix Res Inst, Biol Technol Lab, Chiba 2920812, Japan Helix Res Inst Chiba Japan 2920812 iol Technol Lab, Chiba 2920812, Japan Aisin Cosmos R&D Co Ltd, Biotechnol & Med Engn Field, Chiyoda Ku, Tokyo 1010021, Japan Aisin Cosmos R&D Co Ltd Tokyo Japan 1010021 oda Ku, Tokyo 1010021, Japan Univ Tokyo, Inst Med Sci, Dept Virol, Minato Ku, Tokyo 1088639, Japan UnivTokyo Tokyo Japan 1088639 pt Virol, Minato Ku, Tokyo 1088639, Japan Tokyo Med & Dent Univ, Med Res Inst, Dept Biol Cybernet, Bunkyo Ku, Tokyo 1138510, Japan Tokyo Med & Dent Univ Tokyo Japan 1138510 unkyo Ku, Tokyo 1138510, Japan
Titolo Testata:
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
fascicolo: 2-3, volume: 1489, anno: 1999,
pagine: 421 - 427
SICI:
0167-4781(199912)1489:2-3<421:CAEPOM>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE LYMPHOBLASTIC-LEUKEMIA; ACUTE PROMYELOCYTIC LEUKEMIA; T-CELL LEUKEMIA; ZINC-FINGER; CHROMOSOME-TRANSLOCATION; SEQUENCE MOTIF; TAL-1 GENE; RAR-ALPHA; CHILDHOOD; LOCALIZATION;
Keywords:
zinc finger motif; RING-H2 finger motif; chromosome 1p31-p32; RH mapping; RNF11/Rnf11;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Saito, T Natl Inst Radiol Sci, Genome Res Grp, Inage Ku, Anagawa 4-9-1, Chiba 2638555, Japan Natl Inst Radiol Sci Anagawa 4-9-1 Chiba Japan 2638555 55, Japan
Citazione:
N. Seki et al., "Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein", BBA-GENE ST, 1489(2-3), 1999, pp. 421-427

Abstract

The RING finger (C3HC4-type zinc finger) is a variant zinc finger motif presents in a new family of proteins. A new member of the RING finger family was identified and its cDNA structures were determined in human and mouse. The predicted protein consisting of a 144 amino acid residues is very conservative between the two species and contains a canonical RING-H2 finger motif (C3H2C2) at the carboxyl-terminal region. The genes were designated as RNF11/Rnf11 for RING finger protein 11. A single 2.4-kb transcript of mouse Rnf11 was ubiquitously expressed in various fetal and adult mouse tissues by the Northern blot analysis. The human RNF11 gene was mapped on chromosome1p31-p32 region, where frequent alterations have been observed in T-cell acute lymphoblastic leukemia. (C) 1999 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 07:05:58