Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ALTERED PATTERNS OF CEREBRAL-ACTIVITY DURING SPEECH AND LANGUAGE PRODUCTION IN DEVELOPMENTAL STUTTERING - AN H-2 O-15 POSITRON EMISSION TOMOGRAPHY STUDY
Autore:
BRAUN AR; VARGA M; STAGER S; SCHULZ G; SELBIE S; MAISOG JM; CARSON RE; LUDLOW CL;
Indirizzi:
NIDCD,NIH,LANGUAGE SECT,BLDG 10,ROOM 5N118A BETHESDA MD 20892 NIDCD,NIH,VOICE & SPEECH SECT,VOICE SPEECH & LANGUAGE BRANCH BETHESDAMD 20892 NIMH,NIH,LAB PHYSIOL & PSYCHOPATHOL BETHESDA MD 20892 NIH,CTR CLIN,PET IMAGING SECT BETHESDA MD 20892
Titolo Testata:
Brain
, volume: 120, anno: 1997,
parte:, 5
pagine: 761 - 784
SICI:
0006-8950(1997)120:<761:APOCDS>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
OLD-WORLD MONKEY; ELECTRICAL-STIMULATION; BLOOD-FLOW; FRONTAL-LOBE; FUNCTIONAL-ANATOMY; CHILD STUTTERERS; CINGULATE CORTEX; SENTENCE LENGTH; NORMAL SPEAKERS; PREMOTOR AREAS;
Keywords:
DYSFLUENCY; LATERALIZATION; AUDITORY; FRONTAL; PARALIMBIC;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
120
Recensione:
Indirizzi per estratti:
Citazione:
A.R. Braun et al., "ALTERED PATTERNS OF CEREBRAL-ACTIVITY DURING SPEECH AND LANGUAGE PRODUCTION IN DEVELOPMENTAL STUTTERING - AN H-2 O-15 POSITRON EMISSION TOMOGRAPHY STUDY", Brain, 120, 1997, pp. 761-784

Abstract

To assess dynamic brain function in adults who had stuttered since childhood, regional cerebral blood flow (rCBF) was measured with H2O andPET during a series of speech and language tasks designed to evoke orattenuate stuttering. Speech samples were acquired simultaneously andquantitatively compared with the PET images. Both hierarchical task contrasts and correlational analyses (rCBF versus weighted measures of dysfluency) were performed. rCBF patterns in stuttering subjects differed markedly during the formulation and expression of language, failing to demonstrate left hemispheric lateralization typically observed incontrols; instead regional responses were either absent, bilateral orlateralized to the right hemisphere. Significant differences were detected between groups when all subjects were fluent-during both language formulation and nonlinguistic oral motor tasks-demonstrating that cerebral function may be fundamentally different in persons who stutter;even in the absence of stuttering. Comparison of scans acquired during fluency versus dysfluency-evoking tasks suggested that during the production of stuttered speech, anterior forebrain regions-which play ana role in the regulation of motor function-are disproportionately active in stuttering subjects, while post-rolandic regions-which play a role in perception and decoding of sensory information-are relatively silent. Comparison of scans aqcuired during these conditions in controlsubjects, which provide information about the sensorimotor or cognitive features of the language tasks themselves, suggest a mechanism by which fluency-evoking manoeuvers might differentially affect activity in these anterior and posterior brain regions and may thus facilitate fluent speech production in individuals who stutter Both correlational and contrast analyses suggest that right and left hemispheres play distinct and opposing roles in the generation of stuttering symptoms: activation of left hemispheric regions appears to be related to the production of stuttered speech, while activation of right hemispheric regions may represent compensatory processes associated with attenuation ofstuttering symptoms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 04:32:40