Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Age-related heaving changes and effects of exotoxin on inner ear function in aging rat - A frequency-specific auditory brainstem response study
Autore:
Stenqvist, M;
Indirizzi:
Univ Uppsala Hosp, Akad Sjukhuset, Dept Otorhinolaryngol Head & Neck Surg,S-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden S-75185 ck Surg,S-75185 Uppsala, Sweden
Titolo Testata:
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES
fascicolo: 1, volume: 62, anno: 2000,
pagine: 13 - 19
SICI:
0301-1569(200001/02)62:1<13:AHCAEO>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
COCHLEAR PATHOLOGY; STEM RESPONSES; TUNING CURVES; OTITIS-MEDIA; HAIR CELL; STIMULI; YOUNG;
Keywords:
aging; rat; auditory evoked potential; presbyacusis; exotoxin; Pseudomonas aeruginosa; tuning curve;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Stenqvist, M Univ Uppsala Hosp, Akad Sjukhuset, Dept Otorhinolaryngol Head& Neck Surg,S-75185 Uppsala, Sweden Univ Uppsala Hosp Uppsala Sweden S-75185 85 Uppsala, Sweden
Citazione:
M. Stenqvist, "Age-related heaving changes and effects of exotoxin on inner ear function in aging rat - A frequency-specific auditory brainstem response study", ORL-J OTO R, 62(1), 2000, pp. 13-19

Abstract

Frequency-specific auditory brainstem responses to tone bursts (2-31.5 kHz) and tuning curves were recorded in 8 male rats during their entire life. No significant threshold elevation occurred during the 1st year. Mean age at onset of hearing loss was 20 months, with individual variations ranging from 14 up to 23 months. In most animals, threshold elevations were limited to 20 and 31.5 kHz. At age of 18-23 months, 3 rats were treated with Pseudomonas aeruginosa exotoxin A. After instillation, threshold elevation occurred at all frequencies, followed by near-total recovery at low frequencies, but only partial reversibility at high frequencies. It is concluded that aging-related hearing changes in Sprague-Dawley albino rats start at different ages, particularly comprising high frequencies and encroaching on the middle and tow areas with increasing age. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 22:23:14