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Titolo:
DISSOCIABLE EFFECTS OF SELECTIVE LESIONS TO HIPPOCAMPAL SUBSYSTEMS ONEXPLORATORY-BEHAVIOR, CONTEXTUAL LEARNING, AND SPATIAL-LEARNING
Autore:
GOOD M; HONEY RC;
Indirizzi:
UNIV WALES COLL CARDIFF,SCH PSYCHOL,TOWER BLDG,PK PL CARDIFF CF1 3YG S GLAM WALES
Titolo Testata:
Behavioral neuroscience
fascicolo: 3, volume: 111, anno: 1997,
pagine: 487 - 493
SICI:
0735-7044(1997)111:3<487:DEOSLT>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
LATENT INHIBITION; IBOTENATE LESIONS; NEURONAL LOSS; RATS; FEAR; COMPONENTS; SUBICULUM; AMYGDALA; CORTEX; FORNIX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
M. Good e R.C. Honey, "DISSOCIABLE EFFECTS OF SELECTIVE LESIONS TO HIPPOCAMPAL SUBSYSTEMS ONEXPLORATORY-BEHAVIOR, CONTEXTUAL LEARNING, AND SPATIAL-LEARNING", Behavioral neuroscience, 111(3), 1997, pp. 487-493

Abstract

Rats received excitotoxic lesions of different subsystems within the hippocampal system either the hippocampus proper (cornu ammonis and dentate gyrus; hippocampal lesions) or the entorhinal cortex-subicular region (entorhinal lesions). Subsequently, their activity in an operantchamber was monitored both before and after footshock had been delivered (Experiment 1). Rats with hippocampal lesions showed enhanced activity before the delivery of footshock and reduced freezing after the delivery of shock. Rats with entorhinal lesions showed control levels of activity before the delivery of footshock and control levels of freezing after the delivery of footshock. Both types of lesion impaired spatial learning in a water maze (Experiment 2). These results suggest that the deficits arising from damage to the hippocampal system in contextual and spatial learning have different origins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 10:14:23