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Titolo:
Esophagectomy after induction chemoradiation
Autore:
DeCamp, MM; Swanson, SJ; Jaklitsch, MT;
Indirizzi:
Cleveland Clin Fdn, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44195 USACleveland Clin Fdn Cleveland OH USA 44195 c Surg, Cleveland, OH 44195 USA Brigham & Womens Hosp, Div Thorac Surg, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 orac Surg, Boston, MA 02115 USA
Titolo Testata:
CHEST
fascicolo: 6, volume: 116, anno: 1999, supplemento:, S
pagine: 466S - 469S
SICI:
0012-3692(199912)116:6<466S:EAIC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIMODALITY THERAPY; SQUAMOUS-CELL; CARCINOMA; ESOPHAGUS; ADENOCARCINOMA; SURGERY; CANCER; CHEMOTHERAPY; RADIOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: DeCamp, MM Cleveland Clin Fdn, Dept Thorac & Cardiovasc Surg, 9500 Euclid Ave, Cleveland, OH 44195 USA Cleveland Clin Fdn 9500 Euclid Ave Cleveland OH USA 44195 5 USA
Citazione:
M.M. DeCamp et al., "Esophagectomy after induction chemoradiation", CHEST, 116(6), 1999, pp. 466S-469S

Abstract

The definition of a standard therapy for resectable esophageal cancer remains a clinical controversy. In the past decade, a variety of strategies have been developed in an attempt to improve local control and decrease the all too common problem of distant metastases. Preoperative treatment with radiotherapy or chemotherapy has been proved to be feasible, although neither strategy has resulted in improved survival rates. More recently, concurrent, neoadjuvant chemoradiation has been utilized with encouraging pathologic responses. Equally important is the recognition that such aggressive therapy does not lead to worse surgical outcomes, The evidence for the safety, feasibility, and efficacy of induction therapy followed by esophagectomy is presented in the context of developing a rational methodology to allow for the ongoing modification of standards of care in the management of this difficult disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:41:32