Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Comparison of the effects of desflurane and isoflurane anaesthesia on hepatocellular function assessed by alpha glutathione S-transferase
Autore:
Schmidt, CC; Suttner, SW; Piper, SN; Nagel, D; Boldt, J;
Indirizzi:
Hosp City Ludwigshafen, Dept Anaesthesiol, D-67063 Ludwigshafen, Germany Hosp City Ludwigshafen Ludwigshafen Germany D-67063 udwigshafen, Germany Hosp City Ludwigshafen, Dept Clin Chem, D-67063 Ludwigshafen, Germany HospCity Ludwigshafen Ludwigshafen Germany D-67063 udwigshafen, Germany
Titolo Testata:
ANAESTHESIA
fascicolo: 12, volume: 54, anno: 1999,
pagine: 1207 - 1211
SICI:
0003-2409(199912)54:12<1207:COTEOD>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM ALANINE AMINOTRANSFERASE; IMMUNOHISTOCHEMICAL LOCALIZATION; SENSITIVE MARKER; BLOOD-FLOW; HALOTHANE; INTEGRITY; DAMAGE; ANESTHESIA; ENFLURANE; RATS;
Keywords:
inhalational anaesthesia, desflurane, isoflurane; hepatocellular function, alpha glutathione; S-transferase, aminotransferase;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Schmidt, CC Hosp City Ludwigshafen, Dept Anaesthesiol, Bremserstr 79, D-67063 Ludwigshafen, Germany Hosp City Ludwigshafen Bremserstr 79 Ludwigshafen Germany D-67063
Citazione:
C.C. Schmidt et al., "Comparison of the effects of desflurane and isoflurane anaesthesia on hepatocellular function assessed by alpha glutathione S-transferase", ANAESTHESIA, 54(12), 1999, pp. 1207-1211

Abstract

The purpose of this study was to investigate the influence of isoflurane and desflurane on hepatocellular function. Twenty male patients undergoing elective surgery were randomly assigned to receive either isoflurane or desflurane anaesthesia. Alpha glutathione S-transferase concentrations and aminotransferase activities were measured at induction of anaesthesia (t(0)), 15 min (t(1)), 90 min after induction (t(2)),end of surgery (t(3)) and 2 h thereafter (t(4)). A significant increase in alpha glutathione S-transferaseconcentration was observed only in the isoflurane group. Alpha glutathioneS-transferase levels increased significantly from 2.3 mu gl(-1) at t(0) to6.1 (1.9) mu g.l(-1) at t(2) and to 7.8 (2.1) mu g.l(-1) at t(3). A significant difference in alpha glutathione S-transferase concentration between the two groups was found at t(2) and t(3). The significant increases in alpha glutathione S-transferase concentrations in patients receiving isofluranesuggest a transient disturbance of hepatocellular function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 11:15:05