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Titolo:
Relationship between liver gamma-glutamyltranspeptidase activity and glutathione content in chronic-malnourished pups of adolescent rats
Autore:
de Oliveira, IMV; Fujimori, E; Pereira, VG; Lima, AR;
Indirizzi:
Univ Sao Paulo, Sch Nursing, Dept Publ Hlth, Nutr Lab, BR-05508 Sao Paulo,Brazil Univ Sao Paulo Sao Paulo Brazil BR-05508 Lab, BR-05508 Sao Paulo,Brazil
Titolo Testata:
NUTRITION RESEARCH
fascicolo: 1, volume: 20, anno: 2000,
pagine: 103 - 111
SICI:
0271-5317(200001)20:1<103:RBLGAA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTAMYL-TRANSPEPTIDASE; CYST(E)INE RESERVOIR; HEPATIC GLUTATHIONE; TISSUE GLUTATHIONE; DIETARY-PROTEIN; DEFICIENCY; DEPLETION; PREGNANCY; CYSTEINE; GROWTH;
Keywords:
liver gamma-glutamyltranspeptidase; liver glutathione; chronic protein deficiency; suckling pups; growing rats; adolescent dams;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: de Oliveira, IMV Univ Sao Paulo, Escola Enfermagem, Dept Enfermagem Saude Colet, Lab Nutr, Av Dr Eneas de Carvalho Aguiar 419, BR-05403000 Sao Paulo,Brazil Univ Sao Paulo Av Dr Eneas de Carvalho Aguiar 419 Sao Paulo BrazilBR-05403000 BC
Citazione:
I.M.V. de Oliveira et al., "Relationship between liver gamma-glutamyltranspeptidase activity and glutathione content in chronic-malnourished pups of adolescent rats", NUTR RES, 20(1), 2000, pp. 103-111

Abstract

Liver gamma-glutamyltranspetidase (GGT-EC 2.3.2.2) activity and reduced glutathione (GSH) levels were measured for male pups of adolescent rats on three occasions: delivery day (dl), in the middle of lactation (d10), and after weaning (d50). Pups were weaned on the same diets received:by their mothers during gestation and up to the 10th day of lactation. Diets varied in protein content: 13% and 6% casein. Immediately after birth (dl of lactation), high levels of enzyme activity were observed in all pups, but these levels had sharply decreased by d10. A significant rise in the pups' GGT activity was produced by protein restriction at dl and d50. GSH was also significantly reduced by protein deprivation at dl and d50. A clear interrelationship between liver GGT activity and GSH content could only be established for50 day-old rats. These results indicate that chronic protein malnutrition exerts a special influence on both parameters in the growth period after weaning. (C) 1999 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 12:00:09