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Titolo:
Scopolamine augments transient auditory 40-Hz magnetic response in humans
Autore:
Ahveninen, J; Tiitinen, H; Hirvonen, J; Pekkonen, E; Huttunen, J; Kaakkola, S; Jaaskelainen, IP;
Indirizzi:
Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 it, FIN-00014 Helsinki, Finland Univ Helsinki, Cent Hosp, Med Engn Ctr, BioMag Lab, Helsinki, Finland UnivHelsinki Helsinki Finland Engn Ctr, BioMag Lab, Helsinki, Finland Univ Helsinki, Cent Hosp, Dept Clin Neurosci, Helsinki, Finland Univ Helsinki Helsinki Finland p, Dept Clin Neurosci, Helsinki, Finland
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 2, volume: 277, anno: 1999,
pagine: 115 - 118
SICI:
0304-3940(199912)277:2<115:SATA4M>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
VISUAL-CORTEX; 40 HZ; SYNCHRONIZATION; OSCILLATIONS; CAT;
Keywords:
40-Hz response; acetylcholine; auditory; event-related potentials; magnetoencephalography; muscarinic transmission; scopolamine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Ahveninen, J Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, POB 13, FIN-00014 Helsinki, Finland Univ Helsinki POB 13 Helsinki Finland FIN-00014nki, Finland
Citazione:
J. Ahveninen et al., "Scopolamine augments transient auditory 40-Hz magnetic response in humans", NEUROSCI L, 277(2), 1999, pp. 115-118

Abstract

The influence of neocortical muscarinic transmission on auditory-evoked 40-Hz magnetic response was studied in 13 healthy subjects in a double-blind randomized cross-over design. Either a centrally (scopolamine hydrobromide,0.3 mg, i.v.) or a peripherally (glycopyrrolate, 0.2 mg, i.v.) acting antagonist of muscarinic transmission was administered during two sessions of magnetoencephalographic recording of 40-Hz response elicited by monaural tones. Scopolamine significantly (P < 0.01) augmented the 40-Hz magnetic response over the hemispheres ipsi- and contralateral to the ear stimulated. This finding suggests muscarinic modulation of the auditory evoked transient 40-Hz response. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 17:19:07