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Titolo:
Comparing the effects of nasal synchronized intermittent positive pressureventilation (nSIPPV) and nasal continuous positive airway pressure (nCPAP)after extubation in very low birth weight infants
Autore:
Moretti, C; Gizzi, C; Papoff, P; Lampariello, S; Capoferri, M; Calcagnini, G; Bucci, G;
Indirizzi:
Univ Rome La Sapienza, Dept Pediat, Div Neonatol, I-00161 Rome, Italy UnivRome La Sapienza Rome Italy I-00161 v Neonatol, I-00161 Rome, Italy Univ Rome La Sapienza, Dept Comp Sci & Syst, I-00161 Rome, Italy Univ RomeLa Sapienza Rome Italy I-00161 Sci & Syst, I-00161 Rome, Italy
Titolo Testata:
EARLY HUMAN DEVELOPMENT
fascicolo: 2-3, volume: 56, anno: 1999,
pagine: 167 - 177
SICI:
0378-3782(199912)56:2-3<167:CTEONS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATIENT-TRIGGERED VENTILATION; MECHANICAL VENTILATION; MANDATORY VENTILATION; RESPIRATORY-DISTRESS; CONTROLLED TRIAL;
Keywords:
nasal synchronized intermittent positive pressure ventilation; nasal continuous positive airway pressure; very low birth weight infants; ventilatory support;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Moretti, C Univ Rome La Sapienza, Dept Pediat, Div Neonatol, Viale R Elena324, I-00161 Rome, Italy Univ Rome La Sapienza Viale R Elena 324 Rome Italy I-00161 aly
Citazione:
C. Moretti et al., "Comparing the effects of nasal synchronized intermittent positive pressureventilation (nSIPPV) and nasal continuous positive airway pressure (nCPAP)after extubation in very low birth weight infants", EAR HUM DEV, 56(2-3), 1999, pp. 167-177

Abstract

In this study we hypothesized that nasal synchronized intermittent positive pressure ventilation (nSIPPV) would provide more ventilatory support thannasal continuous positive airway pressure (nCPAP) in the immediate post-extubation period in very low birth weight (VLBW) infants. We tested this hypothesis by comparing the effects of these two ventilatory techniques on ventilation, gas exchange, and patient inspiratory effort in 11 preterm infants immediately after extubation. All neonates studied (BW: 1141+/-(SEM) 53 g; GA: 28.1+/-(SEM) 0.5 wks) had received mechanical ventilation because of respiratory distress at birth and were extubated by day 14 of life. Nasal SIPPV and nCPAP were applied in random order to each infant after extubationso that each was his/her own control. Both nCPAP and nSIPPV were deliveredat end-expiratory pressures (PEEP) of 3 cm H2O. Inspiratory times (Ti) andpeak inspiratory pressures set during nSIPPV were the same as those used at the time of extubation. Recordings lasted 45 min in each mode of ventilation. Tidal volume (Vt), minute volume (Ve), respiratory rate (RR), airway pressure (Paw), transcutaneous PO2 (TcPO2) and PCO2 (TcPCO2) as well as phasic esophageal pressure deflections (Pe), as an estimate of inspiratory effort, were measured. The measurements obtained during both modes of ventilation indicated significant differences between the two techniques. Indeed, application of nSIPPV was associated with a statistically significant increase in Vt and Ve. In addition, Pe decreased by 30% during nSIPPV (P < 0.01). TcPCO2, was statistically significantly lower during nSIPPV than nCPAP, andRR as well. These data therefore suggest that nSIPPV may provide more ventilatory support than nCPAP in the post-extubation period with less patient inspiratory effort. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 05:11:40