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Titolo:
Acute renal failure in a patient with Rosai-Dorfman disease
Autore:
Lai, FMM; To, KF; Szeto, CC; Wang, AYM; Ahuja, AT; Choi, PCL; Leung, CB; Kew, J; Li, PKT;
Indirizzi:
Prince Wales Hosp, Dept Anat & Cellular Pathol, Hong Kong, Peoples R ChinaPrince Wales Hosp Hong Kong Peoples R China Hong Kong, Peoples R China Chinese Univ Hong Kong, Dept Anat & Cellular Pathol, Hong Kong, Hong Kong Chinese Univ Hong Kong Hong Kong Hong Kong Pathol, Hong Kong, Hong Kong Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong ChineseUniv Hong Kong Hong Kong Hong Kong rapeut, Hong Kong, Hong Kong Chinese Univ Hong Kong, Dept Diagnost Radiol & Organ Imaging, Hong Kong, Hong Kong Chinese Univ Hong Kong Hong Kong Hong Kong maging, Hong Kong, Hong Kong
Titolo Testata:
AMERICAN JOURNAL OF KIDNEY DISEASES
fascicolo: 3, volume: 34, anno: 1999,
pagine: E121 - E126
SICI:
0272-6386(199909)34:3<E121:ARFIAP>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MASSIVE LYMPHADENOPATHY; SINUS HISTIOCYTOSIS; EXTRANODAL VARIANT; LYMPHOMA;
Keywords:
Rosai-Dorfman disease; lymphadenopathy; pseudolymphoma; emperipolesis; acute renal failure; renal biopsy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Lai, FMM Prince Wales Hosp, Dept Anat & Cellular Pathol, Room 34055, Hong Kong, Peoples R China Prince Wales Hosp Room 34055 Hong Kong Peoples R China R China
Citazione:
F.M.M. Lai et al., "Acute renal failure in a patient with Rosai-Dorfman disease", AM J KIDNEY, 34(3), 1999, pp. E121-E126

Abstract

Acute renal failure developed in a 57-year-old woman who had Rosai-Dorfmandisease diagnosed 1 year previously on a cervical lymph node. Organ imaging showed diffuse masses infiltrating both kidneys. The renal biopsy showed a lymphoplasmacytic and histiocytic process extensively replacing the parenchyma, which is in keeping with Rosai-Dorfman disease of the kidneys. However, the typical lymphophagocytic cells were lacking. This case illustrates that diagnosis of Rosai-Dorfman disease in renal biopsy can be very difficult, requiring both exclusion of many benign and malignant lesions and a high index of suspicion for this condition. In particular, lymphoma was excluded based on the mixed polyclonal composition of inflammatory cells and the absence of atypical lymphoid proliferation. The renal function partially recovered after a course of therapy combining VP-16 (etoposide) and dexamethasone and remained stable over 4-year follow-up. This report emphasizes the importance of early diagnosis and intervention to safeguard renal function in extensive Rosai-Dorfman disease. (C) 1999 by the National Kidney Foundation, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:30:27