Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Familial gastric cancer: overview and guidelines for management
Autore:
Caldas, C; Carneiro, F; Lynch, HT; Yokota, J; Wiesner, GL; Powell, SM; Lewis, FR; Huntsman, DG; Pharoah, PDP; Jankowski, JA; MacLeod, P; Vogelsang, H; Keller, G; Park, KGM; Richards, FM; Maher, ER; Gayther, SA; Oliveira, C; Grehan, N; Wight, D; Seruca, R; Roviello, F; Ponder, BAJ; Jackson, CE;
Indirizzi:
Cambridge Inst Med Res, Dept Oncol, Cambridge CB2 2XY, England Cambridge Inst Med Res Cambridge England CB2 2XY bridge CB2 2XY, England Univ Cambridge, Addenbrookes Hosp, Strangeways Res Labs, Cambridge CB2 2XY, England Univ Cambridge Cambridge England CB2 2XY abs, Cambridge CB2 2XY, England IPATIMUP, P-4200 Oporto, Portugal IPATIMUP Oporto Portugal P-4200IPATIMUP, P-4200 Oporto, Portugal Univ Porto, Fac Med, P-4200 Oporto, Portugal Univ Porto Oporto Portugal P-4200 orto, Fac Med, P-4200 Oporto, Portugal Creighton Univ, Dept Prevent Med & Publ Hlth, Omaha, NE 68178 USA Creighton Univ Omaha NE USA 68178 nt Med & Publ Hlth, Omaha, NE 68178 USA Natl Inst Canc Res, Chuo Ku, Tokyo 1040045, Japan Natl Inst Canc Res Tokyo Japan 1040045 es, Chuo Ku, Tokyo 1040045, Japan Case Western Reserve Univ, Dept Genet, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Case Western Reserve Univ, Ctr Human Genet, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Univ Hosp Cleveland, Cleveland, OH 44106 USA Univ Hosp Cleveland Cleveland OH USA 44106 eland, Cleveland, OH 44106 USA Univ Virginia, Div Gastroenterol, Charlottesville, VA 22906 USA Univ Virginia Charlottesville VA USA 22906 Charlottesville, VA 22906 USA Henry Ford Hosp, Dept Surg, Detroit, MI 48202 USA Henry Ford Hosp DetroitMI USA 48202 sp, Dept Surg, Detroit, MI 48202 USA Henry Ford Hosp, Dept Med Genet, Detroit, MI 48202 USA Henry Ford Hosp Detroit MI USA 48202 ept Med Genet, Detroit, MI 48202 USA Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC V6H 3V4, Canada Univ British Columbia Vancouver BC Canada V6H 3V4 ver, BC V6H 3V4, Canada Univ Birmingham, Dept Med, Birmingham B15 2TG, W Midlands, England Univ Birmingham Birmingham W Midlands England B15 2TG W Midlands, England Univ Birmingham, Dept Med Genet, Birmingham B15 2TG, W Midlands, England Univ Birmingham Birmingham W Midlands England B15 2TG W Midlands, England Victoria Gen Hosp, Genet Sect, Victoria, BC V8Z 6R5, Canada Victoria Gen Hosp Victoria BC Canada V8Z 6R5 Victoria, BC V8Z 6R5, Canada Tech Univ Munich, Dept Pathol, D-81675 Munich, Germany Tech Univ Munich Munich Germany D-81675 Pathol, D-81675 Munich, Germany Tech Univ Munich, Dept Surg, D-81675 Munich, Germany Tech Univ Munich Munich Germany D-81675 pt Surg, D-81675 Munich, Germany Aberdeen Royal Infirm, Dept Surg, Aberdeen AB9 2ZB, Scotland Aberdeen Royal Infirm Aberdeen Scotland AB9 2ZB erdeen AB9 2ZB, Scotland Addenbrookes Hosp, Dept Pathol, Cambridge CB2 2QQ, England Addenbrookes Hosp Cambridge England CB2 2QQ , Cambridge CB2 2QQ, England Univ Siena, Ist Policattedra Sci Chirurg, I-53100 Siena, Italy Univ SienaSiena Italy I-53100 attedra Sci Chirurg, I-53100 Siena, Italy
Titolo Testata:
JOURNAL OF MEDICAL GENETICS
fascicolo: 12, volume: 36, anno: 1999,
pagine: 873 - 880
SICI:
0022-2593(199912)36:12<873:FGCOAG>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
E-CADHERIN GENE; COLORECTAL-CANCER; TOTAL GASTRECTOMY; BODY-COMPOSITION; CARCINOMA; STOMACH; MUTATIONS; RISK; RECONSTRUCTION; EXPERIENCE;
Keywords:
gastric cancer; familial; hereditary; E-cadherin;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Caldas, C Cambridge Inst Med Res, Dept Oncol, Cambridge CB2 2XY, England Cambridge Inst Med Res Cambridge England CB2 2XY 2XY, England
Citazione:
C. Caldas et al., "Familial gastric cancer: overview and guidelines for management", J MED GENET, 36(12), 1999, pp. 873-880

Abstract

Families with autosomal dominant inherited predisposition to gastric cancer have been described. More recently, germline E-cadherin/CDH1 mutations have been identified in hereditary diffuse gastric cancer kindred. The need to have protocols to manage and counsel these families in the clinic led a group of geneticists, gastro enterologists, surgeons, oncologists, pathologists, and molecular biologists to convene a workshop to produce consensus statements and guidelines for familial gastric cancer. Review of the available cancer pathology from people belonging to families with documented germline E-cadherin/CDH1 mutations confirmed that the gastric cancers were all ofthe diffuse type. Criteria to define the different types of familial gastric cancer syndromes were agreed. Foremost among these criteria was that review of histopathology should be part of the evaluation of any family with aggregation of gastric cancer cases. Guidelines for genetic testing and counselling in hereditary diffuse gastric cancer were produced. Finally, a proposed strategy for clinical management in families with high penetrance autosomal dominant predisposition to gastric cancer was defined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 17:25:49