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Titolo:
Contemporary management of cystinuria
Autore:
Ng, CS; Streem, SB;
Indirizzi:
Cleveland Clin Fdn, Dept Urol, Cleveland, OH 44195 USA Cleveland Clin FdnCleveland OH USA 44195 t Urol, Cleveland, OH 44195 USA
Titolo Testata:
JOURNAL OF ENDOUROLOGY
fascicolo: 9, volume: 13, anno: 1999,
pagine: 647 - 651
SICI:
0892-7790(199911)13:9<647:CMOC>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LASER LITHOTRIPSY; URINARY CYSTINE; HETEROZYGOUS CYSTINURIA; HOMOZYGOUS CYSTINURIA; D-PENICILLAMINE; CALCULI; NEPHROLITHIASIS; CAPTOPRIL; ACETYLCYSTEINE; UROLITHIASIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Streem, SB Cleveland Clin Fdn, Dept Urol, Desk A100,9500 Euclid Ave, Cleveland, OH 44195 USA Cleveland Clin Fdn Desk A100,9500 Euclid Ave Cleveland OH USA 44195
Citazione:
C.S. Ng e S.B. Streem, "Contemporary management of cystinuria", J ENDOUROL, 13(9), 1999, pp. 647-651

Abstract

Cystinuria is an autosomal recessive disorder characterized by a defect inintestinal and renal tubular transport of dibasic amino acids which results in excessive urinary excretion of cystine, Because of the relative insolubility of cystine in urine, patients with this condition are prone to recurrent stone formation. Medical therapy aims both to decrease the urinary concentration of cystine and to increase its solubility, Standard prevention and treatment regimens include hydration, moderate salt and protein restriction, oral alkalinization, and thiol derivatives, Despite aggressive medicalmanagement, however, cystinuric patients are likely to suffer frequent recurrent episodes of stones necessitating urologic intervention. Fortunately,the application of safe and efficacious minimally invasive modalities, including advancements in shockwave lithotripsy, ureteroscopic lithotripsy, and percutaneous nephrolithotomy, have obviated open operative intervention in nearly all cases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:42:17