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Titolo:
Etiology of early age onset substance use disorder: A maturational perspective
Autore:
Tarter, R; Vanyukov, M; Giancola, P; Dawes, M; Blackson, T; Mezzich, A; Clark, DB;
Indirizzi:
Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA Western Psychiat Inst & Clin Pittsburgh PA USA 15213 sburgh, PA 15213 USA Univ Pittsburgh, Sch Med, CEDAR, Dept Psychiat, Pittsburgh, PA 15260 USA Univ Pittsburgh Pittsburgh PA USA 15260 sychiat, Pittsburgh, PA 15260 USA Univ Kentucky, Dept Psychol, Lexington, KY 40506 USA Univ Kentucky Lexington KY USA 40506 ept Psychol, Lexington, KY 40506 USA Penn State Univ, Dept Human Dev & Family Studies, University Pk, PA 16802 USA Penn State Univ University Pk PA USA 16802 s, University Pk, PA 16802 USA
Titolo Testata:
DEVELOPMENT AND PSYCHOPATHOLOGY
fascicolo: 4, volume: 11, anno: 1999,
pagine: 657 - 683
SICI:
0954-5794(199923)11:4<657:EOEAOS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEFICIT HYPERACTIVITY DISORDER; DINUCLEOTIDE REPEAT POLYMORPHISM; D2-DOPAMINE RECEPTOR GENE; CHILD-BEHAVIOR PROBLEMS; ADOLESCENT ALCOHOL-USE; MONOAMINE-OXIDASE-A; HIGH-RISK; DRUG-USE; ANTISOCIAL-BEHAVIOR; PREADOLESCENT BOYS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
183
Recensione:
Indirizzi per estratti:
Indirizzo: Tarter, R Western Psychiat Inst & Clin, 3811 OHara St, Pittsburgh, PA 15213 USA Western Psychiat Inst & Clin 3811 OHara St Pittsburgh PA USA 15213
Citazione:
R. Tarter et al., "Etiology of early age onset substance use disorder: A maturational perspective", DEV PSYCHOP, 11(4), 1999, pp. 657-683

Abstract

The etiology of early age onset substance use disorder (SUD), an Axis I psychiatric illness, is examined from the perspective of the multifactorial model of complex disorders. Beginning:at,conception,genetic and environment interactions produce a sequence of biobehavioral phenotypes during development which bias the ontogenetic pathway toward SUD. One pathway to SUD is theorized to emanate from a deviation in somatic and neurological maturation,which, in the context of adverse environments, predisposes to affective and behavioral dysregulation as the cardinal SUD liability-contributing phenotype. Dysregulation progresses via epigenesis from difficult temperament ininfancy to conduct problems in childhood to substance use by early adolescence and to severe SUD by young adulthood.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 17:07:28