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Titolo:
Diagnosis of malaria: a review of alternatives to conventional microscopy
Autore:
Hanscheid, T;
Indirizzi:
Univ Hosp Santa Maria, Dept Clin Pathol, Haematol Lab, P-1699 Lisbon, Portugal Univ Hosp Santa Maria Lisbon Portugal P-1699 ab, P-1699 Lisbon, Portugal
Titolo Testata:
CLINICAL AND LABORATORY HAEMATOLOGY
fascicolo: 4, volume: 21, anno: 1999,
pagine: 235 - 245
SICI:
0141-9854(1999)21:4<235:DOMARO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYMERASE-CHAIN-REACTION; PLASMODIUM-FALCIPARUM INFECTION; ANTIGEN-CAPTURE ASSAY; DIPSTICK TEST; LACTATE-DEHYDROGENASE; BLOOD-SAMPLES; IMMUNOCHROMATOGRAPHIC TEST; LABORATORY DIAGNOSIS; PARASIGHT(TM)-F TEST; IMPORTED MALARIA;
Keywords:
malaria diagnosis; new techniques; microscopy; antigen-detection; PCR; fluorescent microscopy; imported malaria;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
77
Recensione:
Indirizzi per estratti:
Indirizzo: Hanscheid, T Univ Hosp Santa Maria, Dept Clin Pathol, Haematol Lab, Piso 7, P-1699 Lisbon, Portugal Univ Hosp Santa Maria Piso 7 Lisbon Portugal P-1699 Portugal
Citazione:
T. Hanscheid, "Diagnosis of malaria: a review of alternatives to conventional microscopy", CLIN LAB H, 21(4), 1999, pp. 235-245

Abstract

Malaria causes significant morbidity and mortality worldwide, including countries with mainly imported malaria. In developing nations, scarce resources lead to inadequate diagnostic procedures. In affluent countries, poor familiarity with malaria may cause clinical and laboratory misdiagnosis. Microscopy of Giemsa-stained thick and thin films remains the current standard for diagnosis. Although it has good sensitivity and allows species identification and parasite counts, it is time consuming, requires microscopical expertise and maintenance of equipment. Microscopy with fluorescent stains (QBC (R)), dipstick antigen detection of HRP2 and pLDH (Parasight (R)-F, ICT Malaria Pf (R), OptiMAL (R)), polymerase chain reaction assays and some automated blood cell analysers offer new approaches and are reviewed here, with emphasis on clinical relevance and their potential to complement conventional microscopy, especially in countries with imported malaria.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 10:35:26