Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
BLUNT TRAUMA AND OPERATIVE CARE IN MICROGRAVITY - A REVIEW OF MICROGRAVITY PHYSIOLOGY AND SURGICAL INVESTIGATIONS WITH IMPLICATIONS FOR CRITICAL CARE AND OPERATIVE TREATMENT IN-SPACE
Autore:
KIRKPATRICK AW; CAMPBELL MR; NOVINKOV OL; GONCHAROV IB; KOVACHEVICH IV;
Indirizzi:
UNIV TORONTO,DEPT CRIT CARE,100 COLL ST TORONTO ON CANADA UNIV TORONTO,DEPT GEN SURG TORONTO ON CANADA MCCAISTON REG MED CTR,DEPT GEN SURG PARIS FRANCE NASA,LYNDON B JOHNSON SPACE CTR,KRUG LIFE SCI,MED OPERAT BRANCH HOUSTON TX 77058 MINIST PUBL HLTH RUSSIA,INST BIOMED PROBLEMS,MED OPERAT BRANCH MOSCOWRUSSIA
Titolo Testata:
Journal of the American College of Surgeons
fascicolo: 5, volume: 184, anno: 1997,
pagine: 441 - 453
SICI:
1072-7515(1997)184:5<441:BTAOCI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
FATALLY INJURED PATIENTS; DAMAGE CONTROL; SUSTAINED MICROGRAVITY; THORACOABDOMINAL TRAUMA; ABBREVIATED LAPAROTOMY; ABDOMINAL-TRAUMA; SKELETAL-MUSCLE; IN-SPACE; SURGERY; SPACEFLIGHT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
120
Recensione:
Indirizzi per estratti:
Citazione:
A.W. Kirkpatrick et al., "BLUNT TRAUMA AND OPERATIVE CARE IN MICROGRAVITY - A REVIEW OF MICROGRAVITY PHYSIOLOGY AND SURGICAL INVESTIGATIONS WITH IMPLICATIONS FOR CRITICAL CARE AND OPERATIVE TREATMENT IN-SPACE", Journal of the American College of Surgeons, 184(5), 1997, pp. 441-453

Abstract

BACKGROUND: The assembly of the International Space Station in a low earth orbit will soon become a reality. The National Aeronautics and Space Administration envisions inhabited lunar bases and staffed missions to Mars in the future. Increasing numbers of astronauts, construction of high-mass structures, increased extra-vehicular activity, and prolonged if not prohibitive medical evacuation times to earth underscore the need to address requirements for trauma care in nonterrestrial environments. STUDY DESIGN: A search was carried out to review the relevant literature in the MEDLINE and SPACELINE databases. All related Technical, Corporate, and Flight Test Reports in the KRUG Life Sciences corporate library were also reviewed. Bibliographies of all articles were then reviewed from these papers to identify additional pertinent literature. Senior Russian investigators reviewed the Russian literature and translated Russian publications when appropriate. Personal communication and discussion with active microgavity investigators and ongoing microgravity research supplemented published reports. RESULTS: A large volume of data exist to document the multiple detrimental physiologic effects of microgravity exposure on human physiology. Organs systems such as cardiovascular, neurohumoral, immune, hematopoetic, and musculoskeletal systems map be particularly affected. These physiologic changes suggest an impaired ability to withstand major systemic trauma. Observational data also suggest adverse changes in numerous aspects of response to wounding and injury, and in areas such as the behavior of hemorrhage, microbiologic flora, and wound healing. In addition to an increased volume of ongoing and anticipated basic science research in microgravity physiology, preliminary studies of clinical diagnosis and therapy have been carried out in microgravity and microgravity laboratories. The feasibility of a wide range of ancillary critical care techniques has been verified in the parabolic flight model of microgravity. Although Russian investigators first performed laparotomies on rabbits in parabolic flight in 1967, only recently have American investigators demonstrated the reproducible feasibility of open and endoscopic surgical procedures under general anesthetic in animal models in a microgravity environment. CONCLUSIONS: With appropriate instrumentation and personnel, the majority of resuscitative and surgical interventions required to stabilize a severely injured astronaut are feasible ina microgravity environment. Onboard limitations in mass, volume, and power that are ever present in any spacecraft design will limit the realistic capabilities of the medical system. Standard proved and testedtrauma and operative management protocols will constitute the basis for extra-terrestrial care. Surgeons should familiarize themselves withthe microgravity environment and remain active in planning trauma care for the continued exploration of space.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 18:18:02