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Titolo:
Urinary calcium excretion in healthy children and adolescents
Autore:
Manz, F; Kehrt, R; Lausen, B; Merkel, A;
Indirizzi:
Res Inst Child Nutr, D-44225 Dortmund, Germany Res Inst Child Nutr Dortmund Germany D-44225 , D-44225 Dortmund, Germany
Titolo Testata:
PEDIATRIC NEPHROLOGY
fascicolo: 9, volume: 13, anno: 1999,
pagine: 894 - 899
SICI:
0931-041X(199911)13:9<894:UCEIHC>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
IDIOPATHIC HYPERCALCIURIA; SCHOOL-CHILDREN; URIC-ACID; METABOLISM; MAGNESIUM; OXALATE; VALUES; GIRLS;
Keywords:
urinary calcium excretion; hypercalciuria; calcium intake; age; sex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Manz, F Res Inst Child Nutr, D-44225 Dortmund, Germany Res Inst Child Nutr Dortmund Germany D-44225 5 Dortmund, Germany
Citazione:
F. Manz et al., "Urinary calcium excretion in healthy children and adolescents", PED NEPHROL, 13(9), 1999, pp. 894-899

Abstract

Urinary calcium (Ca excretion was determined in 1,578 24-h urine samples from 507 healthy children and adolescents (252 boys, 255 girls; 2.8-18.4 years) participating in the DONALD Study and is presented for 32 different ageand sex groups. Calciuria values related to body weight (mg/kg per day) were relatively constant except for a transient decrease during puberty in all centiles, with a later onset in boys than girls. Distribution of calciuria (mg/kg per day) was best normalized by log transformation, with an almostconstant standard deviation of the log-transformed values. Ca excretion was greater than or equal to 4 mg/kg per day in 8.6% and greater than or equal to 6 mg/kg per day in 1.5% of the urine samples. Based on Ca excretion rates of 1,080 pairs of 24-h urine samples from 364 children and adolescents,sensitivity, specificity, and the predictive value for hypercalciuria (greater than or equal to 4 mg/kg per day) in the next urine sample were calculated at three test levels classifying calciuria of the initial urine sample. In summary, this study presents normal values of urinary Ca excretion related to age and sex in a population of healthy German children and adolescents consuming a typical western-style diet. A high level of calciuria in a random urine sample is important in the diagnosis of hypercalciuria.

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Documento generato il 29/11/20 alle ore 00:42:10