Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Detection of myocardial viability by low-dose dobutamine cine MR imaging
Autore:
Sandstede, JJW; Bertsch, G; Beer, M; Kenn, W; Werner, E; Pabst, T; Lipke, C; Kretschmer, S; Neubauer, S; Hahn, D;
Indirizzi:
Univ Wuerzburg, Inst Roentgendiagnost, D-97080 Wuerzburg, Germany Univ Wuerzburg Wuerzburg Germany D-97080 ost, D-97080 Wuerzburg, Germany Univ Wuerzburg, Med Klin, D-97080 Wuerzburg, Germany Univ Wuerzburg Wuerzburg Germany D-97080 lin, D-97080 Wuerzburg, Germany Univ Wuerzburg, Nukl Med Klin & Poliklin, D-97080 Wuerzburg, Germany Univ Wuerzburg Wuerzburg Germany D-97080 lin, D-97080 Wuerzburg, Germany
Titolo Testata:
MAGNETIC RESONANCE IMAGING
fascicolo: 10, volume: 17, anno: 1999,
pagine: 1437 - 1443
SICI:
0730-725X(199912)17:10<1437:DOMVBL>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; POSITRON EMISSION TOMOGRAPHY; LEFT-VENTRICULAR DYSFUNCTION; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; SUCCESSFUL REVASCULARIZATION; F-18 FLUORODEOXYGLUCOSE; STRESS ECHOCARDIOGRAPHY; HIBERNATING MYOCARDIUM; VIABLE MYOCARDIUM; INFARCTION;
Keywords:
cardiac imaging; stress MR imaging; myocardial viability;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Sandstede, JJW Univ Wuerzburg, Inst Roentgendiagnost, Josef Schneider Str 2, D-97080 Wuerzburg, Germany Univ Wuerzburg Josef Schneider Str 2 Wuerzburg Germany D-97080
Citazione:
J.J.W. Sandstede et al., "Detection of myocardial viability by low-dose dobutamine cine MR imaging", MAGN RES IM, 17(10), 1999, pp. 1437-1443

Abstract

The purpose of this work was to test the diagnostic value of dobutamine stress magnetic resonance imaging (MRI) for predicting recovery of regional myocardial contractility after revascularization. Cardiac wall motion abnormalities are due to either non-viable and/or scarred, or viable, but hibernating, myocardial tissue. Dobutamine stress leads to increased systolic wallthickening only in viable myocardium. Twenty-five patients with akinetic or dyskinetic myocardial regions were examined with a Cine FLASH-2D sequenceat rest and during dobutamine stress (10 mu g/kg/min). Patients were re-examined at rest 3, and ist case of persisting wall motion defects, 6 months after revascularization. Criterion of viability was increasing end-systolicwall thickening during stress and/or at follow-up. Akinetic regions related either to the LAD (n = 19) or to the RCA (n = 6) were judged viable if >=50% of the affected segments improved. MR studies were completed in all subjects without arrhythmia or need for early terminations due to symptoms. Sensitivity, specificity, and positive predictive value for the prediction ofmyocardial viability were 61%, 90%, and 87% for the segment-related analysis, and 76%, 100%, and 100% for the patient-related analysis based on coronary artery distribution, respectively. Dobutamiue stress MRI allows to predict global functional recovery of akinetic myocardial regions after revascularization with a high positive predictive value and high specificity. (C) 1999 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 04:21:02