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Titolo:
Mannose metabolism and carbohydrate deficient glycoprotein syndrome type I
Autore:
Seta, N; Dupre, T; Cormier-Daire, V; de Lonlay, P; Moore, S; Durand, G; Codogno, P;
Indirizzi:
Hop Bichat, F-75877 Paris 18, France Hop Bichat Paris France 18Hop Bichat, F-75877 Paris 18, France
Titolo Testata:
M S-MEDECINE SCIENCES
fascicolo: 11, volume: 15, anno: 1999,
pagine: 1202 - 1210
SICI:
0767-0974(199911)15:11<1202:MMACDG>2.0.ZU;2-W
Fonte:
ISI
Lingua:
FRE
Soggetto:
POLYMANNOSE-TYPE OLIGOSACCHARIDES; LINKED OLIGOSACCHARIDE; ENDOPLASMIC-RETICULUM; RAT-LIVER; N-GLYCOSYLATION; HEPG2 CELLS; TRANSPORT; GLUCOSE; MEMBRANE; CYTOSOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Seta, N Hop Bichat, 46 Rue Henri Huchard, F-75877 Paris 18, France Hop Bichat 46 Rue Henri Huchard Paris France 18 Paris 18, France
Citazione:
N. Seta et al., "Mannose metabolism and carbohydrate deficient glycoprotein syndrome type I", M S-MED SCI, 15(11), 1999, pp. 1202-1210

Abstract

Monosaccharide mannose is a constituent of glycoproteins bearing N-linked oligosaccharide chains and the glycolipid anchors that enable proteins without membrane spanning domains to associate with cellular membranes. With, on the one hand, the description of Carbohydrate-Deficient Glycoprotein Syndrome (CDGS), a group of metabolic diseases in which glycoprotein biosynthesis is severely impaired, and, on the other, the recent identification of specific mannose transporters, our view of the metabolism of mannose, and itsrelationship with glucose metabolism is changing. These new insights into the metabolism or mannose has led to the proposal of therapies for cer taintypes cif CDGS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 19:29:00