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Titolo:
Impaired skin microcirculation and blood rheology in patients with monoclonal gammapathy
Autore:
Szulkowska, E; Sulek, K; Kraj, M; Budziszewska, K; Zygocki, K;
Indirizzi:
Mil Med Sch, Dept Clin Haematol, PL-00909 Warsaw, Poland Mil Med Sch Warsaw Poland PL-00909 lin Haematol, PL-00909 Warsaw, Poland Inst Hematol & Blood Transfusiol, Hematol Clin, Warsaw, Poland Inst Hematol & Blood Transfusiol Warsaw Poland tol Clin, Warsaw, Poland
Titolo Testata:
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
fascicolo: 2, volume: 21, anno: 1999,
pagine: 105 - 112
SICI:
1386-0291(1999)21:2<105:ISMABR>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTOCCLUSIVE REACTIVE HYPEREMIA; LASER-DOPPLER; HYPERVISCOSITY SYNDROMES; CLINICAL MANIFESTATIONS; VISCOSITY;
Keywords:
monoclonal gammapathy; blood rheology; skin microcirculation; laser Doppler flowmetry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Sulek, K Mil Med Sch, Dept Clin Haematol, Szaserow 128 Str, PL-00909 Warsaw, Poland Mil Med Sch Szaserow 128 Str Warsaw Poland PL-00909 rsaw, Poland
Citazione:
E. Szulkowska et al., "Impaired skin microcirculation and blood rheology in patients with monoclonal gammapathy", CL HEMORH M, 21(2), 1999, pp. 105-112

Abstract

Hemorheological disturbances in patients with monoclonal gammapathies are widely known, but there is little information about microcirculation in these patients. The following study was performed to examine skin microcirculation and its relationship with blood rheology. We analysed both haematological and hemorheological parameters (blood and plasma viscosity, aggregationindex and filterability of 1 mi of whole blood) and skin microcirculation in 46 patients with monoclonal gammapathy and 22 healthy controls. Microcirculation on dorsal aspect of the hand was examined with laser Doppler flowmeter. We measured resting flow and biological zero and maximal flow during postischemic hyperaemic reaction after one minute occlusion on the arm. Thesame parameters were estimated for CMBC (concentration of moving blood cells). Patients with monoclonal gammapathy are characterised by statisticallyhigher whole blood and plasma viscosities and other hemorheological parameters and disturbed skin microcirculation expressed as statistically significant lower resting flux and impaired reaction for temporary occlusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:29:42