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Titolo:
Chemosensory signaling in C-elegans
Autore:
Troemel, ER;
Indirizzi:
Univ Calif San Francisco, Dept Anat, Program Biol Sci, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Univ Calif San Francisco, Dept Biochem, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
BIOESSAYS
fascicolo: 12, volume: 21, anno: 1999,
pagine: 1011 - 1020
SICI:
0265-9247(199912)21:12<1011:CSIC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEMATODE CAENORHABDITIS-ELEGANS; PUTATIVE PHEROMONE RECEPTORS; CYCLOPHILIN HOMOLOG NINAA; NUCLEOTIDE-GATED CHANNEL; DAUER LARVA FORMATION; MULTIGENE FAMILY; ODORANT RECEPTOR; DEFECTIVE-MUTANTS; OLFACTORY NEURONS; SENSORY NEURONS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
65
Recensione:
Indirizzi per estratti:
Indirizzo: Troemel, ER Univ Calif San Francisco, Dept Anat, Program Biol Sci, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 94143 USA
Citazione:
E.R. Troemel, "Chemosensory signaling in C-elegans", BIOESSAYS, 21(12), 1999, pp. 1011-1020

Abstract

The nematode Caenorhabditis elegans can sense and respond to hundreds of different chemicals with a simple nervous system, making it an excellent model for studies of chemosensation. The chemosensory neurons that mediate responses to different chemicals have been identified through laser ablation studies, providing a cellular context for chemosensory signaling. Genetic and molecular analyses indicate that chemosensation in nematodes involves G protein signaling pathways, as it does in vertebrates, but the receptors andG proteins involved belong to nematode-specific gene families. It is likely that about 500 different chemosensory receptors are used to detect the large spectrum of chemicals to which C. elegans responds, and one of these receptors has been matched with its odorant ligand. C. elegans olfactory responses are also subject to regulation based on experience, allowing the nematode to respond to a complex and changing chemical environment. BioEssays 21:1011-1020, 1999. (C) 1999 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 03:54:49