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Titolo:
Chronic cholestatic disorders in adults.
Autore:
Chazouilleres, O;
Indirizzi:
Hop St Antoine, Serv Hepatol & Gastroenterol, F-75571 Paris 12, France HopSt Antoine Paris France 12 & Gastroenterol, F-75571 Paris 12, France
Titolo Testata:
PATHOLOGIE BIOLOGIE
fascicolo: 9, volume: 47, anno: 1999,
pagine: 974 - 982
SICI:
0369-8114(199911)47:9<974:CCDIA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
FRE
Soggetto:
PRIMARY BILIARY-CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; ORTHOTOPIC LIVER-TRANSPLANTATION; URSODEOXYCHOLIC ACID THERAPY; CONTROLLED TRIAL; AUTOIMMUNE HEPATITIS; NATURAL-HISTORY; EFFICACY; MECHANISMS; VALIDATION;
Keywords:
chronic cholestasis; primary biliary cirrhosis; primary sclerosing cholangitis; ursodeoxycholic acid;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Chazouilleres, O Hop St Antoine, Serv Hepatol & Gastroenterol, 184 Rue Faubourg St Antoine,F-75571 Paris 12, France Hop St Antoine 184 Rue Faubourg St Antoine Paris France 12
Citazione:
O. Chazouilleres, "Chronic cholestatic disorders in adults.", PATH BIOL, 47(9), 1999, pp. 974-982

Abstract

Many hepatobiliary diseases can result in cholestasis. The main causes of chronic cholestasis in adults are primary biliary cirrhosis, which is characterized by portal triad inflammation and segmental necrosis of interlobular bile ducts, and primary sclerosing cholangitis, in which the intra and/orextrahepatic bile ducts undergo inflammation and fibrosis. The diagnosis is based on the presence of evidence of cholestasis and of symptoms specificfor each condition. A number of drugs, sarcoidosis, total parenteral nutrition, chronic liver transplant rejection, and graft-versus-host disease canalso cause chronic cholestasis. The treatment of these conditions has benefited greatly from rational use of ursodeoxycholic acid.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:58:45