Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Growth factor therapy to the damaged inner ear: clinical prospects
Autore:
Malgrange, B; Rigo, JM; Van de Water, TR; Staecker, H; Moonen, G; Lefebvre, PP;
Indirizzi:
Univ Liege, Dept Human Physiol & Pathophysiol, B-4020 Liege, Belgium Univ Liege Liege Belgium B-4020 ol & Pathophysiol, B-4020 Liege, Belgium Univ Liege, Dept Otorhinolaryngol, B-4020 Liege, Belgium Univ Liege Liege Belgium B-4020 Otorhinolaryngol, B-4020 Liege, Belgium Albert Einstein Coll Med, Dept Neurosci, Bronx, NY 10467 USA Albert Einstein Coll Med Bronx NY USA 10467 Neurosci, Bronx, NY 10467 USA Albert Einstein Coll Med, Dept Otolaryngol, Bronx, NY 10467 USA Albert Einstein Coll Med Bronx NY USA 10467 laryngol, Bronx, NY 10467 USA Harvard Univ, Massachusetts Eye & Ear Infirm, Sch Med, Boston, MA USA Harvard Univ Boston MA USA tts Eye & Ear Infirm, Sch Med, Boston, MA USA
Titolo Testata:
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
, volume: 49, anno: 1999, supplemento:, 1
pagine: S19 - S25
SICI:
0165-5876(19991005)49:<S19:GFTTTD>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUDITORY HAIR-CELLS; SENSORY EPITHELIA; DEVELOPING ORGAN; ACOUSTIC TRAUMA; RETINOIC ACID; REGENERATION; NEURONS; PROLIFERATION; SURVIVAL; CULTURE;
Keywords:
cell culture; cochlea; hearing impairment; inner ear; ototoxicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Lefebvre, PP Univ Liege, Dept Human Physiol & Pathophysiol, Pl Delcour 17,B-4020 Liege, Belgium Univ Liege Pl Delcour 17 Liege Belgium B-4020 Liege, Belgium
Citazione:
B. Malgrange et al., "Growth factor therapy to the damaged inner ear: clinical prospects", INT J PED O, 49, 1999, pp. S19-S25

Abstract

Most hearing loss results from lesions of the sensory cells and/or of the neurons of the auditory part of the inner ear. There is currently no treatment able to stop the progression of a hearing loss or to restore a lost auditory function. In this paper, we review the progress which has been made with respect to the regeneration and the protection of the hair cells and ofthe auditory neurons in the cochlea. In particular, we emphasize the control by growth factors of the protection/repair mechanisms of the neurosensory structures within the inner ear, in the prospect of the possible clinicaluse of these molecules. Finally, we discuss the different approaches whichcan be used to deliver these therapeutic agents to the inner ear. (C) 1999Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 20:43:54