Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Preparation and characterisation of gels based on sucrose modified with glycidyl methacrylate
Autore:
Ferreira, L; Vidal, MM; Geraldes, CFGC; Gil, MH;
Indirizzi:
Univ Coimbra, Dept Engn Quim, P-3000 Coimbra, Portugal Univ Coimbra Coimbra Portugal P-3000 Engn Quim, P-3000 Coimbra, Portugal Univ Coimbra, Dept Bioquim, P-3000 Coimbra, Portugal Univ Coimbra Coimbra Portugal P-3000 t Bioquim, P-3000 Coimbra, Portugal
Titolo Testata:
CARBOHYDRATE POLYMERS
fascicolo: 1, volume: 41, anno: 2000,
pagine: 15 - 24
SICI:
0144-8617(200001)41:1<15:PACOGB>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHEMOENZYMATIC SYNTHESIS; ENZYMATIC-SYNTHESIS; HYDROGELS; RELEASE; DRUG; RESOLUTION; SPECTRA; MEDIA;
Keywords:
sucrose; glycidyl methacrylate; gels; swelling; drug release;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Gil, MH Univ Coimbra, Dept Engn Quim, Largo Marques Pombal, P-3000 Coimbra, Portugal Univ Coimbra Largo Marques Pombal Coimbra Portugal P-3000 ortugal
Citazione:
L. Ferreira et al., "Preparation and characterisation of gels based on sucrose modified with glycidyl methacrylate", CARBOHY POL, 41(1), 2000, pp. 15-24

Abstract

Sugar-based hydrogels were prepared by non-selective modification of sucrose with the introduction of vinyl groups. Sucrose was reacted with glycidylmethacrylate (1:1 molar ratio) in DMSO and in the presence of 4-(N,N-dimethylamino)pyridine (4-DMAP) as catalyst. The structure of the product (SucMA) was established using H-1 NMR, H-1 DQF-COSY NMR and C-13 NMR analysis. Gels were prepared by copolymerisation of hydroxyethyl methacrylate (HEMA) and SucMA in a 70:30 ethylene glycol/water mixed solvent using ammonium persulphate/sodium methabisulphite pair as initiating system. The swelling behaviour of these gels was evaluated as a function of crosslinker content, copolymer composition, pH and ionic strength. In addition, the diffusional behaviour of sodium salycilate (SSA) from these gels and poly(HEMA) gels is also reported. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 06:27:03