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Titolo:
PSYCHIATRIC CORRELATES OF MR DEEP WHITE-MATTER LESIONS IN PROBABLE ALZHEIMERS-DISEASE
Autore:
LOPEZ OL; BECKER JT; REYNOLDS CF; JUNGREIS CA; WEINMAN S; DEKOSKY ST;
Indirizzi:
NEUROPSYCHOL RES PROGRAM,3600 FORBES AVE,SUITE 502 PITTSBURGH PA 15213 UNIV PITTSBURGH,SCH MED,DEPT NEUROL PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,DEPT PSYCHIAT PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,DEPT RADIOL NEURORADIOL PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,DEPT NEUROSURG PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,ALZHEIMERS DIS RES CTR PITTSBURGH PA 15261 UNIV PITTSBURGH,SCH MED,MENTAL HLTH CLIN RES CTR LATE LIFE MOOD DISORDERS PITTSBURGH PA 15261
Titolo Testata:
The Journal of neuropsychiatry and clinical neurosciences
fascicolo: 2, volume: 9, anno: 1997,
pagine: 246 - 250
SICI:
0895-0172(1997)9:2<246:PCOMDW>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARKINSONS-DISEASE; LEUKO-ARAIOSIS; DEMENTIA; DEPRESSION; LUCENCIES; HYPERINTENSITIES; ABNORMALITIES; COGNITION; DISORDERS; DIAGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
O.L. Lopez et al., "PSYCHIATRIC CORRELATES OF MR DEEP WHITE-MATTER LESIONS IN PROBABLE ALZHEIMERS-DISEASE", The Journal of neuropsychiatry and clinical neurosciences, 9(2), 1997, pp. 246-250

Abstract

The authors examined the relationship between psychiatric symptoms and the presence of MR deep white matter lesions (DWMLs) in 28 probable Alzheimer's disease (AD) patients with mild to moderate dementia. The difference in frequency of psychiatric symptoms between patients with and without DWMLs was not statistically significant. However, MR global scores of severity correlated with the presence of ideational disturbances (such as low self-esteem and suicidal ideation). Analysis of specific cerebral regions indicated that the highest correlation occurred in the frontal white matter. Thus, DWMLs are correlated with specific symptoms of depression in AD. Whether DWMLs are etiologically related to these symptoms remains to be determined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 16:05:25