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Titolo: Long term improvement of hematopoiesis following cyclosporine treatment ina patient with myelodysplastic syndrome
Autore: Berer, A; Ohler, L; Simonitsch, I; Thalhammer, R; Lechner, K; Geissler, K;
- Indirizzi:
- Univ Vienna, Div Hematol & Blood Coagulat, Dept Med 1, Dept Lab Med,Dept Clin Pathol, A-1010 Vienna, Austria Univ Vienna Vienna Austria A-1010 pt Clin Pathol, A-1010 Vienna, Austria
- Titolo Testata:
- WIENER KLINISCHE WOCHENSCHRIFT
fascicolo: 19,
volume: 111,
anno: 1999,
pagine: 815 - 818
- SICI:
- 0043-5325(19991015)111:19<815:LTIOHF>2.0.ZU;2-F
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- TUMOR-NECROSIS-FACTOR; BONE-MARROW; INTERFERON-GAMMA; IMMUNOLOGICAL ABNORMALITIES; SPONTANEOUS REMISSION; PROGENITOR CELLS; APLASTIC-ANEMIA; INHIBITION; LEUKEMIA; THERAPY;
- Keywords:
- myelodysplastic syndrome; cyclosporine;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Clinical Medicine
- Citazioni:
- 25
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Berer, A Innere Med Klin 1, Hamatol Abt, Wahringer Gurtel 18-20, A-1090 Vienna, Austria Innere Med Klin 1 Wahringer Gurtel 18-20 Vienna Austria A-1090 a
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- Citazione:
- A. Berer et al., "Long term improvement of hematopoiesis following cyclosporine treatment ina patient with myelodysplastic syndrome", WIEN KLIN W, 111(19), 1999, pp. 815-818
Abstract
Current treatment of patients with myelodysplastic syndrome (MDS) is unsatisfactory. Very recently, immunosuppressive treatment strategies have been gaining interest. We report a patient with transfusion-dependent MDS who achieved significant hematopoietic improvement following cyclosporine (CsA) therapy and who is now transfusion independent for more than 5 years. This single observation supports the view that CsA, among other immunosuppressiveagents, could play an important role in future treatment concepts in MDS and may lead to clinically relevant and sustained improvement of hematopoiesis in a subset of patients.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 19:01:05