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Titolo:
RISK STRATIFICATION IN UNSTABLE CORONARY-ARTERY DISEASE - ADDITIVE VALUE OF TROPONIN-T DETERMINATIONS AND PREDISCHARGE EXERCISE TESTS
Autore:
LINDAHL B; ANDREN B; OHLSSON J; VENGE P; WALLENTIN L; LUNDIN L; TOSS H; LINDAHL B; LINDSTROM G; SVENSSON E; ALSJO G; SLTRE H; AHLBERG G; HAGSTROM L; SUNDQVIST C; PIHL E; GUSTAFSSON G; LARSSON L; GUSTAVSSON PE; LOFMARK R; LUNDQVIST IB; HAMMARSTROM E; BASTANI H; ENG E; LUNDIN P; REHNQVIST N; AMBRANT B; OBLACK P; HOLMSTRAND M; FJELSTAD B; ARONSON D; OSTBERG S; FRISELL JE; HEDMAN A; SANDSTROM M; PERERS G; IRVING P; ANDERSSON I; HULTING J; HOJIER J; AMANULLAH A; SAMAD B; STEINBRUCK I; EKBLOM M; SWAHN E; KARLSSON E; NIELSEN N; SAFSTROM K; LOGANDER E; FALK SA; FRIDEN J; NILSSON O; RONNHAGEN K; ABOUZEID L; HEDBACK B; PERK J; OSSIANSSONPETTERSSON L; HOLMBERG B; LANDGREN F; RYDEN S; BJURLING E; KARLSSON JE; MALMBERG C; SVENSSON O; SVENSSON E; EKDAHL S; NYMAN I; PANTZAR Y; ENGHOFF E; LUNDSTROM T; ANDREN B; OHLSSON J; WALLENTIN L; OHLSSON J; LINDSTROM G; LOGANDER E; SVENSSON E;
Indirizzi:
UNIV UPPSALA HOSP,DEPT CARDIOL S-75185 UPPSALA SWEDEN UNIV UPPSALA,DEPT CARDIOL UPPSALA SWEDEN UNIV UPPSALA,DEPT CLIN PHYSIOL UPPSALA SWEDEN CTY HOSP RYHOV,DEPT CLIN PHYSIOL JONKOPING SWEDEN UNIV UPPSALA,DEPT CLIN CHEM UPPSALA SWEDEN
Titolo Testata:
European heart journal
fascicolo: 5, volume: 18, anno: 1997,
pagine: 762 - 770
SICI:
0195-668X(1997)18:5<762:RSIUCD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; PROGNOSTIC-SIGNIFICANCE; ANGINA-PECTORIS; Q-WAVE; PATHOGENESIS; MECHANISMS; EPISODE; LESIONS; REST;
Keywords:
UNSTABLE CORONARY ARTERY DISEASE; UNSTABLE ANGINA PECTORIS; NON-Q WAVE MYOCARDIAL INFARCTION; RISK STRATIFICATION; TROPONIN T; EXERCISE TEST;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
B. Lindahl et al., "RISK STRATIFICATION IN UNSTABLE CORONARY-ARTERY DISEASE - ADDITIVE VALUE OF TROPONIN-T DETERMINATIONS AND PREDISCHARGE EXERCISE TESTS", European heart journal, 18(5), 1997, pp. 762-770

Abstract

In 963 patients, participating in a randomized study of low molecularweight heparin in unstable coronary artery disease and followed for 5months, troponin T was determined. In the 766 patients with a pre-discharge exercise test both troponin T level and exercise test response were independent predictors of prognosis. Cardiac death or myocardial infarction occurred in 5, 9 and 13% of the patients with a maximal troponin T level of <0.06 (n=154), 0.06-0.2 (n=175) and greater than or equal to 0.2 mu g.l(-1) (n=437), respectively. Based on exercise tolerance and occurrence of ST depression, patients with a low (n=361), intermediate (n=325) and high risk (n=80) exercise test response were identified. In these, death or myocardial infarction occurred in 5, 13 and29%, respectively. The combination of troponin T and the exercise test response allowed an even better categorization into low (n=84), intermediate (n=406) and high (n=276 risk groups with 1, 7 and 20% death or myocardial infarction, respectively. Among those 197 patients unableto perform an exercise test the incidence was 3, 16 and 27% in patients with troponin T <0.06, 0.06-0.2 and greater than or equal to 0.2 mug.l(-1), respectively. Thus, troponin T determinations and pre-discharge exercise tests alone and combined are valuable for risk assessmentin unstable coronary artery disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 20:42:08