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Titolo:
Circadian variability of late potential analysis in holter electrocardiograms
Autore:
Steinbigler, P; Haberl, R; Jilge, G; Steinbeck, G;
Indirizzi:
Univ Munich, Klinikum Grosshadern, Med Hosp 1, D-81366 Munich, Germany Univ Munich Munich Germany D-81366 , Med Hosp 1, D-81366 Munich, Germany
Titolo Testata:
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
fascicolo: 10, volume: 22, anno: 1999,
pagine: 1448 - 1456
SICI:
0147-8389(199910)22:10<1448:CVOLPA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SIGNAL-AVERAGED ELECTROCARDIOGRAM; VENTRICULAR LATE POTENTIALS; CORONARY-ARTERY DISEASE; SUDDEN CARDIAC DEATH; MYOCARDIAL-INFARCTION; TACHYCARDIA; ISCHEMIA; STIMULATION; ARRHYTHMIAS; INSIGHTS;
Keywords:
Holter monitoring; signal averaging; late potentials; ventricular fibrillation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Steinbigler, P Univ Munich, Klinikum Grosshadern, Med Hosp 1, Marchioninistr 15, D-81366 Munich, Germany Univ Munich Marchioninistr 15 Munich Germany D-81366 rmany
Citazione:
P. Steinbigler et al., "Circadian variability of late potential analysis in holter electrocardiograms", PACE, 22(10), 1999, pp. 1448-1456

Abstract

Appearance of ventricular tachycardia, ventricular fibrillation, and sudden cardiac death has diurnal variations. We retrospectively studied, using digital Holter electrocardiogram, whether a time course in the appearance oflate potentials may be associated with malignant ventricular arrhythmias. The 24-hour recordings in 200 patients after myocardial infarction (50 patients with documented, sustained, monomorphic and reproducibly inducible ventricular tachycardia (< 270/min) (group I;), 50 patients resuscitated from ventricular fibrillation (group II), and 200 patients without ventricular arrhythmias (group III) were divided into 24 segments, 60 minutes each. Latepotential analysis was performed using the Simson method in the time domain in each segment and compared to a conventional short-term registration. Late potential analysis in conventional short-term recordings during arbitrarily chosen daytimes revealed late potentials in 80% of patients in group I, 38% of patients in group II, and in 16% of patients without ventricular arrhythmias. In at least one 60-minute segment late potentials were found ingroup I in 92%, in group II in 88% (P < 0.05 vs conventional analysis), and in group III in 19%. Interestingly, in patients with a history of ventricular fibrillation late potentials appeared significantly more often during morning hours (6-12AM: 82% vs 26% at 12AM-6PM, 30% at 6PM-12PM, and 42% at 12PM-6AM, P < 0.05), especially during phases with heart rate accelerations. Late potential analysis for risk stratification in conventional short-term recordings is feasible for patients prone to ventricular tachycardia, butpatients prone to ventricular fibrillation would be more effectively stratified using 24-hour registrations with detection of circadian variations oflate potential appearance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 15:48:31