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Titolo:
Comorbidities of overweight and obesity: current evidence and research issues
Autore:
Pi-Sunyer, FX;
Indirizzi:
Columbia Univ Coll Phys & Surg, Obes Res Ctr, St Lukes Roosevelt Hosp Ctr,New York, NY 10025 USA Columbia Univ Coll Phys & Surg New York NY USA 10025 w York, NY 10025 USA
Titolo Testata:
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
fascicolo: 11, volume: 31, anno: 1999, supplemento:, S
pagine: S602 - S608
SICI:
0195-9131(199911)31:11<S602:COOAOC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; BODY-FAT DISTRIBUTION; ADIPOSE-TISSUE DISTRIBUTION; CARDIOVASCULAR RISK-FACTORS; ENDOMETRIAL CANCER RISK; DEPENDENT DIABETES-MELLITUS; HIGH-DENSITY LIPOPROTEIN; INTRA-ABDOMINAL FAT; MIDDLE-AGED MEN; BLOOD-PRESSURE;
Keywords:
risk factors; disease; fat; fat distribution;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
159
Recensione:
Indirizzi per estratti:
Indirizzo: Pi-Sunyer, FX Columbia Univ Coll Phys & Surg, Obes Res Ctr, St Lukes Roosevelt Hosp Ctr,1111 Amsterdam Ave, New York, NY 10025 USA Columbia Univ CollPhys & Surg 1111 Amsterdam Ave New York NY USA 10025
Citazione:
F.X. Pi-Sunyer, "Comorbidities of overweight and obesity: current evidence and research issues", MED SCI SPT, 31(11), 1999, pp. S602-S608

Abstract

Purpose: The evidence with regard to the relationship of obesity with medical comorbidities was assessed and priority research issues identified. Methods: The existing literature in English was surveyed. Results: The evidence is overwhelming on the association of obesity to a number of medical conditions. These include: insulin resistance, glucose intolerance, diabetes mellitus, hypertension, dyslipidemia, sleep apnea, arthritis, hyperuricemia, gall bladder disease, and certain types of cancer. The independent association of obesity seems also clearly established for coronary artery disease, heart failure, cardiac arrhythmia, stroke, and menstrual irregularities. The relationship between central (or upper body) obesity and the above conditions is positive for most of them but with a lesser number of studies. Mostof the fat distribution studies have been done using anthropometric measurements rather than the more accurate magnetic resonance imaging or computertomographic scans. Priority research issues include the following: more definitive data on the relation of central fat to comorbidities; the proportional importance of subcutaneous versus visceral fat in producing comorbidities; the relationship between obesity and psychiatric disease; the geneticsof the relationship between obesity and each of the comorbidities; the independent contribution of dirt and of sedentariness to the development of each of the comorbidities; the impact of gender, race, intensity, and duration on these associations. Conclusions: The evidence for the relationship of obesity to a number of comorbidities is strong, though the strength of the relationship varies with the condition, Much more research is necessary on causation and on what other factors may play an interactive role.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:36:49