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Titolo:
Simultaneous HPTLC determination of cinnarizine and domperidone maleate informulations
Autore:
Argekar, AP; Power, SG;
Indirizzi:
Inst Sci, Dept Chem, Analyt Lab, Bombay 400032, Maharashtra, India Inst Sci Bombay Maharashtra India 400032 ombay 400032, Maharashtra, India
Titolo Testata:
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC
fascicolo: 4, volume: 12, anno: 1999,
pagine: 272 - 274
SICI:
0933-4173(199907/08)12:4<272:SHDOCA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Keywords:
HPTLC; cinnarizine; domperidone maleate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Argekar, AP Inst Sci, Dept Chem, Analyt Lab, 15 Madam Cama Rd, Bombay 400032, Maharashtra, India Inst Sci 15 Madam Cama Rd Bombay Maharashtra India 400032 ndia
Citazione:
A.P. Argekar e S.G. Power, "Simultaneous HPTLC determination of cinnarizine and domperidone maleate informulations", J PL CHROM, 12(4), 1999, pp. 272-274

Abstract

A simple, rapid, and precise HPTLC method has been developed for the simultaneous determination of cinnarizine and domperidone maleate. Separations were performed on silica gel 60F(254) HPTLC plates with methanol-dichloromethane-formic acid, 1 + 9 + 0.05 (v/v) as mobile phase. Detection aas performed densitometrically at lambda = 276 nm. Calibration curves for cinnarizineand domperidone maleate were linear in the concentration ranges 60-1000 and 50-1000 ng mu L-1, respectively Assays for cinnarizine and domperidone maleate were 19.92 and 14.97 mg/tablet (RSD 1.1% and 1.02%), respectively forthe brand analyzed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/11/18 alle ore 04:32:54